Skip to Content
Merck
All Photos(1)

Documents

880124P

Avanti

DSPE-PEG(2000) Folate

Avanti Polar Lipids 880124P, powder

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000] (ammonium salt)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

CAS Number:
1236288-25-7
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (880124P-1mg)
pkg of 1 × 10 mg (880124P-10mg)
pkg of 1 × 5 mg (880124P-5mg)

manufacturer/tradename

Avanti Polar Lipids 880124P

shipped in

dry ice

storage temp.

−20°C

Inchi Code

1S/C65H106N9O59P.43C2H4.2H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-57(76)86-49-54(91-58(77)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)50-90-134(83,84)89-44-42-68-65(82)85-45-46-88-93-95-97-99-101-103-105-107-109-111-113-115-117-119-121-123-125-127-129-131-133-132-130-128-126-124-122-120-118-116-114-112-110-108-106-104-102-100-98-96-94-92-87-43-41-67-56(75)40-39-55(63(80)81)72-61(78)51-35-37-52(38-36-51)69-47-53-48-70-60-59(71-53)62(79)74-64(66)73-60;43*1-2;;/h35-38,41,43,48,54-55,69H,3-34,39-40,42,44-47,49-50H2,1-2H3,(H,67,75)(H,68,82)(H,72,78)(H,80,81)(H,83,84)(H3,66,70,73,74,79);43*1-2H2;2*1H3/b43-41-;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/t54-,55+;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/m1............................................./s1

InChI key

MGPKLRBTQDOCPL-KKIWFSQHSA-N

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO/C=C\NC(CC[C@H](NC(C1=CC=C(NCC(C=N2)=NC3=C2N=C(N)NC3=O)C=C1)=O)C([O-])=O)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C

Application

DSPE-PEG(2000) Folate has been mixed in chloroform for folate-targeted PEGylated liposomes preparation.

Biochem/physiol Actions

Folate offers protection against megaloblastic anaemia during pregnancy.

Packaging

5 mL Amber Glass Screw Cap Vial (880124P-10mg)
5 mL Amber Glass Screw Cap Vial (880124P-1mg)
5 mL Amber Glass Screw Cap Vial (880124P-5mg)

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 9

1 of 9

Avanti Polar Lipids 880135P, powder

Avanti

880135P

DSPE-PEG(2000) Carboxylic Acid

DSPE-PEG(2000) Maleimide Avanti Polar Lipids 880126P, powder

Avanti

880126P

DSPE-PEG(2000) Maleimide

Avanti Polar Lipids 880133P, powder

Avanti

880133P

Bis-DSPE PEG2000

Avanti Polar Lipids 880122P, powder

Avanti

880122P

DSPE-PEG(2000) Cyanur

Avanti Polar Lipids 880129C

Avanti

880129C

DSPE-PEG(2000) Biotin

DSPE PEG(2000)-N-Cy5 Avanti Polar Lipids, chloroform solution

Avanti

810891C

DSPE PEG(2000)-N-Cy5

Avanti Polar Lipids

Avanti

850715P

18:0 PE

Sigma-Aldrich

Sigma-Aldrich

F7057

Folate Receptor 2 human

Avanti Polar Lipids 880229P, powder

Avanti

880229P

DSPE-PEG(2000)-DBCO

Microfluidic synthesis of PEG-and folate-conjugated liposomes for one-step formation of targeted stealth nanocarriers
Hood RR, et al.
Pharmaceutical Research, 30(6), 1597-1607 (2013)
Folate and human reproduction.
Tamura T and Picciano MF
American Journal of Clinical Nutrition, 83(5), 993-1016 (2006)
Tomonori Shiokawa et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 11(5), 2018-2025 (2005-03-10)
To establish a novel formulation tumor-targeted drug carrier of lipophilic antitumor antibiotics, aclacinomycin A (ACM), folate-linked microemulsions were prepared and investigated both in vitro and in vivo. Three kinds of folate-linked microemulsions with different polyethylene glycol (PEG) chain lengths loading
Shih-Jiuan Chiu et al.
Journal of controlled release : official journal of the Controlled Release Society, 112(2), 199-207 (2006-03-28)
A novel transferrin receptor (TfR)-targeted liposomal formulation was synthesized and evaluated for the delivery of a phosphorothioate antisense oligodeoxyribonucleotide (ODN) (G3139, oblimerson sodium, or Genasense) to Bcl-2 in K562 leukemia cells. Liposomes composed of DC-Chol/egg PC/PEG-DSPE (25:73.5:1.5, mol/mol/mol) were loaded
A Gabizon et al.
Bioconjugate chemistry, 10(2), 289-298 (1999-03-17)
Conjugates of three components, folic acid-poly(ethylene glycol)-distearoylphosphatidylethanolamine (FA-PEG-DSPE), derived from PEG with molecular masses of 2000 and 3350 Da were synthesized by a carbodiimide-mediated coupling of FA to H2N-PEG-DSPE. The conjugates were characterized by 1H NMR, MALDI-TOF, and HPLC analysis
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service