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810891C

Avanti

DSPE PEG(2000)-N-Cy5

Avanti Polar Lipids, chloroform solution

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000]-N-(Cyanine 5)

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About This Item

Empirical Formula (Hill Notation):
C164H299N4O55P
CAS Number:
2315262-02-1
Molecular Weight:
3238.10
UNSPSC Code:
12352211

Assay

99% (TLC)

form

chloroform solution

packaging

pkg of 1 × 1 mg (
810891C-1MG)
pkg of 5 × 1 mg (
810891C-5MG)

manufacturer/tradename

Avanti Polar Lipids

concentration

1 mg/mL (810891C-1MG)
1 mg/mL (810891C-5MG)

shipped in

dry ice

storage temp.

−20°C

Application

DSPE PEG(2000)-N-Cy5 is suitable for use to ensure the proper insertion of folic acid to red blood cells (RBCs) membrane by fluorescence microscopy.

Biochem/physiol Actions

DSPE PEG(2000)-N-Cy5 is used in the preparation of folic acid and Cy5 modified red blood cells (RBCs) vesicles (FRVs). DSPE PEG(2000)-N-Cy5 is used to demonstrate the modification of RBCs membrane with folic acid. After mixing DSPE PEG(2000)-N-Cy5 with RBC, the non-luminous membrane exhibits bright Cy5 fluorescence, enables visualization with fluorescence microscope.

Packaging

5ML Clear Glass Sealed Ampule (810891C-1MG)
5ML Clear Glass Sealed Ampule (810891C-5MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Engineered red blood cells for capturing circulating tumor cells with high performance
Zhu DM, et al.
Nanoscale, 10(13), 6014-6023 (2018)
Erythrocyte derived vesicles for circulating tumor cells capturing and specific tumor imaging
Liu A, et al.
Nanoscale, 11, 12388-12396 (2019)
Ming Chen et al.
Nanoscale, 11(25), 12388-12396 (2019-06-20)
The precise diagnosis of cancer remains a great challenge; therefore, it is our research interest to develop safe, tumor-specific reagents. In this study, we designed nanovesicles derived from erythrocyte membranes; the nanovesicles are capable of recognizing tumor cells for both

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