880138P
Avanti
DSPE-PEG(2000) Carboxy NHS
Avanti Polar Lipids
Synonym(s):
DSPE-PEG(2000) Carboxy NHS, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000, NHS ester] (sodium salt)
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About This Item
Empirical Formula (Hill Notation):
C135H260N2NaO57P
CAS Number:
Molecular Weight:
2877.45
UNSPSC Code:
12352211
NACRES:
NA.25
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Assay
>99% (TLC)
form
powder
packaging
package of 1 × 10 mg
manufacturer/tradename
Avanti Polar Lipids
application(s)
advanced drug delivery
lipid type
polymerizable lipids
shipped in
dry ice
storage temp.
−20°C
Application
- Enhanced detection of myeloma cells: DSPE-PEG(2000) Carboxy was used to create fluorescence labeled XT5 modified nano-capsules, enhancing the sensitivity of detecting myeloma cells. This application demonstrates its potential in biomedical diagnostics and targeted therapy (Norouz Dizaji et al., 2022).
- Improving drug encapsulation efficiency: The use of DSPE-PEG(2000) Carboxy in pre-formed liposomes for drug delivery showcases a method that significantly improves carboplatin encapsulation, highlighting its role in optimizing chemotherapeutic drug formulations (Wehbe et al., 2017).
- Targeted drug delivery for cardiovascular diseases: DSPE-PEG(2000) Carboxy was integral in the development of PEGylated-nanoliposomal formulations of clusterin, aimed at treating amyloidogenic light chain-induced endothelial dysfunction, underscoring its utility in targeted cardiovascular therapies (Guzman-Villanueva et al., 2018).
Packaging
5 mL Amber Glass Screw Cap Vial (880138P-25MG)
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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