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840457P

Avanti

16:0-18:1 PG

Avanti Polar Lipids

Synonym(s):

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); POPG; PG(16:0/18:1(9Z)); 110650

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About This Item

Empirical Formula (Hill Notation):
C40H76O10PNa
CAS Number:
268550-95-4
Molecular Weight:
770.99
UNSPSC Code:
51191904
NACRES:
NA.25

description

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (840457P-1g)
pkg of 2 × 100 mg (840457P-200mg)
pkg of 5 × 100 mg (840457P-500mg)
pkg of 1 × 25 mg (840457P-25mg)

manufacturer/tradename

Avanti Polar Lipids

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C40H77O10P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(44)50-38(36-49-51(45,46)48-34-37(42)33-41)35-47-39(43)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,37-38,41-42H,3-16,19-36H2,1-2H3,(H,45,46);/q;+1/p-1/b18-17-;/t37?,38-;/m1./s1

InChI key

FJXDNGDRHUDFST-XQYKCTAGSA-M

General description

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores.

Application

16:0-18:1 PG has been used in the preparation of large unilamellar vesicles (LUVs).

Biochem/physiol Actions

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.

Packaging

5 mL Clear Glass Sealed Ampule (840457P-200mg)
5 mL Clear Glass Sealed Ampule (840457P-25mg)
5 mL Clear Glass Sealed Ampule (840457P-500mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (840457P-1g)

also commonly purchased with this product

Product No.
Description
Pricing

700000P

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840034P

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840035P

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850345P

14:0 PC (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine, powder

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16:0 PC (DPPC), Avanti Polar Lipids

850365P

18:0 PC (DSPC), Avanti Polar Lipids

850375P

18:1 (Δ9-Cis) PC (DOPC), Avanti Polar Lipids

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16:0-18:1 PC, Avanti Polar Lipids

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18:1 (Δ9-Cis) PE (DOPE), Avanti Polar Lipids

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16:0 Cardiolipin, Avanti Polar Lipids

100500P

E. coli Extract Total, Avanti Polar Lipids

100600P

E. coli Extract Polar, Avanti Polar Lipids

840051P

Egg PC, Avanti Polar Lipids

610017

Syringe (1000 μL), Avanti Polar Lipids

610000

Extruder Set with Holder/Heating Block, Avanti Polar Lipids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sigma-Aldrich

42773

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Membrane Structure and Dynamics
Cell Biology, 227-239 (2017)
Lipids
Medical Biochemistry, 283(18), 99-119 (2017)
Sandeep Kumar et al.
The journal of physical chemistry. B, 122(26), 6763-6770 (2018-06-08)
The interaction of amphiphilic ionic liquids containing an 1-alkyl-3-methylimidazolium cation ([C12MIM]+), which shows acute cytotoxicity toward marine and bacterial life, with zwitterionic 1-palmitoyl-2-oleoyl- sn-glycero-3-phospho-choline (POPC) and anionic 1-palmitoyl-2-oleoyl- sn-glycero-3-phospho- rac-glycerol (POPG) membranes was investigated. Biophysical parameters of this interaction were
Takeshi Sunami et al.
Langmuir : the ACS journal of surfaces and colloids, 34(1), 88-96 (2017-12-08)
Liposome fusion is a way of supplying additional components for in-liposome biochemical reactions. Electrofusion is a method that does not require the addition of fusogens, which often alter the liposome dispersion, and is therefore useful for repetitive liposome fusion. However
Taiji Okano et al.
ACS synthetic biology, 7(2), 739-747 (2018-02-01)
The shapes of giant unilamellar vesicles (GUVs) enclosing polymer molecules at relatively high concentration, used as a model cytoplasm, significantly differ from those containing only small molecules. Here, we investigated the effects of the molecular weights and concentrations of polymers
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