Skip to Content
Merck
All Photos(2)

Documents

840857P

Avanti

16:0-18:1 PA

powder

Synonym(s):

1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphate (sodium salt); POPA; PA(16:0/18:1(9Z)); 110616

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C37H70O8PNa
CAS Number:
169437-35-8
Molecular Weight:
696.91
UNSPSC Code:
51191904
NACRES:
NA.25

description

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt)

Assay

>99% (TLC)

form

powder

packaging

pkg of 2 × 100 mg (840857P-200mg)
pkg of 5 × 100 mg (840857P-500mg)
pkg of 1 × 25 mg (840857P-25mg)

manufacturer/tradename

Avanti Polar Lipids

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C37H71O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,35H,3-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b18-17-;/t35-;/m1./s1

InChI key

PPYXMAJBOKWTQX-RYRMQHSSSA-M

General description

Phosphatidic acid (PA), the smallest and simplest phospholipid is produced from phosphatidylcholine with the help of phospholipase D. This glycerophospholipid is an ester of glycerol, which possess two long-chain fatty acids (LCFAs) at C1 and C2 and phosphoric acid at C3 positions.

Application

16:0-18:1 PA is suitable for use
  • in liposomes preparation
  • for lipid extraction of mitochondria
  • to generate multilamellar phospholipid vesicles

Biochem/physiol Actions

Phosphatidic acid (PA) may induce negative curvature in the cytoplasmic leaflet of the plasma membrane, which enables the development of the hemi fusion intermediates, that is essential for the fusion of two membranes.

Packaging

5 mL Clear Glass Sealed Ampule (840857P-200mg)
5 mL Clear Glass Sealed Ampule (840857P-25mg)
5 mL Clear Glass Sealed Ampule (840857P-500mg)

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 9

1 of 9

18:1 PA Avanti Polar Lipids

Avanti

840875P

18:1 PA

22:1 (Cis) PC 1,2-dierucoyl-sn-glycero-3-phosphocholine, powder

Avanti

850398P

22:1 (Cis) PC

18:1 PA Avanti Polar Lipids

Avanti

840875C

18:1 PA

16:0-18:1 PG Avanti Polar Lipids

Avanti

840457P

16:0-18:1 PG

16:0-18:1 PC Avanti Polar Lipids

Avanti

850457P

16:0-18:1 PC

18:0 PA Avanti Polar Lipids

Avanti

830865P

18:0 PA

18:1 (Δ9-Cis) PG Avanti Polar Lipids

Avanti

840475P

18:1 (Δ9-Cis) PG

16:0-18:1 PE Avanti Polar Lipids

Avanti

850757C

16:0-18:1 PE

16:0-18:1 PC Avanti Polar Lipids

Avanti

850457C

16:0-18:1 PC

Muscle Lipid Metabolism
Muscle and Exercise Physiology, 271-284 (2019)
Membrane polar lipids
Stillwell W
An Introduction to Biological Membranes: Composition, Structure and Function, 63-87 (2016)
Surfactant protein A (SP-A) binds to phosphatidylserine and competes with annexin V binding on late apoptotic cells
Jakel A, et al.
Protein & cell, 1(2), 188-197 (2010)
The Molecular Mechanisms Underlying Synaptic Transmission: A View of the Presynaptic Terminal
The synapse : structure and function, 1(2), 21-109 (2014)
Mitochondrial translocation of alpha-synuclein is promoted by intracellular acidification
Cole NB, et al.
Experimental Cell Research, 314(10), 2076-2089 (2008)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service