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PHR1741

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2-Chlor-5-Nitrobenzoesäure

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

2-Chlor-5-nitro-benzoesäure

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About This Item

Lineare Formel:
ClC6H3(NO2)CO2H
CAS-Nummer:
2516-96-3
Molekulargewicht:
201.56
Beilstein:
1877474
EG-Nummer:
219-739-7
MDL-Nummer:
MFCD00007294
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329823586
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

300

API-Familie

mesalazine

Analysenzertifikat (CofA)

current certificate can be downloaded

Verpackung

pkg of 200 mg

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

165-168 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

OC(=O)c1cc(ccc1Cl)[N+]([O-])=O

InChI

1S/C7H4ClNO4/c8-6-2-1-4(9(12)13)3-5(6)7(10)11/h1-3H,(H,10,11)

InChIKey

QUEKGYQTRJVEQC-UHFFFAOYSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

2-Chloro-5-nitrobenzoic acid, commonly known as Mesalazine Impurity M, is a related compound of anti-inflammatory agent Mesalazine. Mesalazine belongs to a group of drugs referred to as aminosalicylates and is generally used in the treatment of inflammatory bowel disease.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

2-Chloro-5-nitrobenzoic acid may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA7964 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H317,H319

Gefahreneinstufungen

Eye Irrit. 2 - Skin Sens. 1

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
LRAC5138
LRAA7964

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Mesalazine
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 6962-2066 (2019)
Aminosalicylates in inflammatory bowel disease
Hanauer SB
Alimentary Pharmacology & Therapeutics, 20, 60-65 (2004)

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