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PHR1746

Supelco

4-Aminosalicylsäure

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

4-Amino-salicylsäure, 4-Amino-2-hydroxy-benzoesäure, PAS

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About This Item

Lineare Formel:
H2NC6H3-2-(OH)CO2H
CAS-Nummer:
65-49-6
Molekulargewicht:
153.14
Beilstein:
473071
EG-Nummer:
200-613-5
MDL-Nummer:
MFCD00007789
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329823591

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

300

Agentur

traceable to USP 1026401

API-Familie

aminosalicylic acid

Analysenzertifikat (CofA)

current certificate can be downloaded

Verpackung

pkg of 500 mg

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

135-145 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

Nc1ccc(C(O)=O)c(O)c1

InChI

1S/C7H7NO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,8H2,(H,10,11)

InChIKey

WUBBRNOQWQTFEX-UHFFFAOYSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

4-Aminosalicylic acid is an isomer of 5-ASA, the active component of sulfasalazine. This nonsteroidal anti-inflammatory drug (NSAID) has been used in the treatment of tuberculosis and is also known to be effective in treating distal ulcerative colitis.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA7969 in the slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
LRAC8046
LRAC4388
LRAA7969

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Mesalazin European Pharmacopoeia (EP) Reference Standard

Y0000297

Mesalazin

Salicylsäure Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1013

Salicylsäure

5-Aminosalicylsäure ≥99%

Sigma-Aldrich

A3537

5-Aminosalicylsäure

Placebo-controlled trial of ulcerative colitis with oral 4-aminosalicylic acid
Ginsberg AL, et al.
Gastroenterology, 102(2), 448-452 (1992)

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