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PHR1504

Supelco

Liothyronin

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

3,3′,5-Triiod-L-thyronin, O-(4-Hydroxy-3-iodphenyl)-3,5-diiod-L-tyrosin, Liothyronin, T3

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About This Item

Empirische Formel (Hill-System):
C15H12I3NO4
CAS-Nummer:
6893-02-3
Molekulargewicht:
650.97
Beilstein:
2710227
EG-Nummer:
229-999-3
MDL-Nummer:
MFCD00002593
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329823425
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

300

Agentur

traceable to USP 1368008

API-Familie

liothyronine

Form

solid

Analysenzertifikat (CofA)

current certificate can be downloaded

Verpackung

pkg of 500 mg

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

234-238 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Lagertemp.

2-8°C

SMILES String

N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O

InChI

1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1

InChIKey

AUYYCJSJGJYCDS-LBPRGKRZSA-N

Angaben zum Gen

human ... THRA(7067) , THRB(7068)

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Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC2088 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Ähnliches Produkt

Produkt-Nr.
Beschreibung
Preisangaben

Piktogramme

Health hazard
GHS08

Signalwort

Danger

H-Sätze

H372

Gefahreneinstufungen

STOT RE 1

Lagerklassenschlüssel

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
LRAD3313
LRAC2088
LRAB0433

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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3,3′,5-Triiod-L-thyronin ≥95% (HPLC), powder

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Sigma-Aldrich

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Sigma-Aldrich

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L-Thyroxin

Aoife Parsons et al.
Aquatic toxicology (Amsterdam, Netherlands), 209, 99-112 (2019-02-15)
Brominated flame retardants are known to disrupt thyroid hormone (TH) homeostasis in several vertebrate species, but the molecular mechanisms underlying this process and their effects on TH-sensitive tissues during the stages of early development are not well characterised. In this

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