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LIGHTOX25

Sigma-Aldrich

LightOx™25

≥95% (HPLC)

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About This Item

Empirische Formel (Hill-System):
C21H21NO2
CAS-Nummer:
2342579-17-1
Molekulargewicht:
319.40
UNSPSC-Code:
12352200

Assay

≥95% (HPLC)

Form

powder

Lagertemp.

2-8°C

Inchi Code

1S/C21H21NO2/c1-15(2)22-13-3-4-19-14-17(9-12-20(19)22)6-5-16-7-10-18(11-8-16)21(23)24/h7-12,14-15H,3-4,13H2,1-2H3,(H,23,24)

InChIKey

OWPRYZBCLJMXGR-UHFFFAOYSA-N

Verwandte Kategorien

Anwendung

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

Biochem./physiol. Wirkung

Strong ligand for retinoic acid receptor proteins

Leistungsmerkmale und Vorteile

LightOx25 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx25 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Sonstige Hinweise

Chemical Equivalency 1ea=1mg

Rechtliche Hinweise

LightOx is a trademark of LightOx Ltd.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

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Artikel

Fluorescent Retinoid Probes

Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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