Skip to Content
MilliporeSigma
All Photos(2)

Documents

P3513

Sigma-Aldrich

Poly-L-lysine, succinylated

mol wt >50,000

Synonym(s):

Modified Lysine Copolymer

Sign Into View Organizational & Contract Pricing


About This Item

MDL number:
UNSPSC Code:
12352209
NACRES:
NA.26

form

powder or solid

Quality Level

mol wt

>50,000

color

white to faint yellow

application(s)

cell analysis

storage temp.

−20°C

Looking for similar products? Visit Product Comparison Guide

Application

Succinylated poly-L-lysine has been used to bind (Gly)3-Arg-bradykinin to study its hydrolysis by brain endopeptidases and pancreatic proteinases.

Biochem/physiol Actions

Poly-L-lysine is a cationic polymer. It is mainly used for immobilizing cells to glass substrates or negatively charged substrates.
An intermediate for coupling proteins to poly-L-lysine.

Analysis Note

Molecular weight based on precursor poly-L-lysine viscosity. Also assayed by MALLS.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 6

1 of 6

Poly-L-lysine solution 0.1 % (w/v) in H2O

Sigma-Aldrich

P8920

Poly-L-lysine solution

Poly-L-lysine solution mol wt 150,000-300,000, 0.01%, sterile-filtered, BioReagent, suitable for cell culture

Sigma-Aldrich

P4832

Poly-L-lysine solution

L-Lysine ≥98% (TLC)

Sigma-Aldrich

L5501

L-Lysine

V S Trubetskoy et al.
Nucleic acids research, 27(15), 3090-3095 (1999-08-24)
DNA can be condensed with an excess of poly-cations in aqueous solutions forming stable particles of submicron size with positive surface charge. This charge surplus can be used to deposit alternating layers of polyanions and polycations on the surface surrounding
Topographical Pattern Dynamics in Passive Adhesion of Cell Membranes
Alina Hategan
Biophysical Journal, 87(5), 3547?3560-3547?3560 (2004)
Effects of poly(L-lysine) substrates on attached Escherichia coli bacteria.
Colville K
Langmuir, 26(4), 2639-2644 (2010)
M R Hamblin et al.
British journal of cancer, 89(5), 937-943 (2003-08-28)
Conjugates between photosensitisers (PS) and charged polymeric carriers are under investigation for photodynamic therapy of cancer and may allow targeting to certain cell types or compartments in tumours. Covalent attachment of polyethylene glycol to macromolecules (pegylation) may alter their pharmacokinetics
Susceptibility of a Peptide Derived from Bradykinin to Hydrolysis by Brain Endo-oligopeptidases and Pancreatic Proteinases*
Antonio C. M. Camargo
The Journal of Biological Chemistry, 254(12), 5304-5307 (1979)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service