W450001
Choline chloride
FCC
Synonym(s):
(2-Hydroxyethyl)trimethylammonium chloride
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About This Item
Linear Formula:
(CH3)3N(Cl)CH2CH2OH
CAS Number:
Molecular Weight:
139.62
FEMA Number:
4500
Beilstein/REAXYS Number:
3563126
EC Number:
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
NACRES:
NA.21
Recommended Products
biological source
synthetic
Quality Level
grade
Halal
Kosher
reg. compliance
FCC
FDA 21 CFR 117
form
powder, crystals or chunks
color
white
mp
302-305 °C (dec.) (lit.)
application(s)
flavors and fragrances
documentation
see Safety & Documentation for available documents
food allergen
no known allergens
organoleptic
fishy
SMILES string
[Cl-].C[N+](C)(C)CCO
InChI
1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
InChI key
SGMZJAMFUVOLNK-UHFFFAOYSA-M
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General description
Choline chloride (ChCl) is a quaternary ammonium salt. The unusual solvent properties of eutectic mixtures of urea and choline chloride make it useful as a biodegradable ambient-temperature solvent for a number of applications.
Application
- Profiling and optimized extraction of bioactive polyphenolic compounds from young, red-fleshed apple using eco-friendly deep eutectic solvents.: This research demonstrates the use of choline chloride-based deep eutectic solvents (DES) as a green alternative for extracting polyphenolic compounds from apples. The study highlights DESs effectiveness in yielding high-quality extracts, which could revolutionize natural product extraction processes in the food industry (Yu et al., 2024).
- 17beta-estradiol induces hyperresponsiveness in guinea pig airway smooth muscle by inhibiting the plasma membrane Ca(2+)-ATPase.: This research utilizes choline chloride in physiological experiments to investigate the mechanisms through which estradiol affects calcium signaling in airway smooth muscle. The findings could lead to better understanding and treatment of asthma and other respiratory disorders (Romero-Martinez et al., 2024).
- DES-ultrasonication treatment of cellulose nanocrystals and the reinforcement in carrageenan biocomposite.: In this study, choline chloride is used to create a novel biocomposite material, demonstrating its potential in enhancing the mechanical properties of biodegradable plastics. This could lead to new advancements in sustainable material science (Ramli et al., 2024).
- A sensitive determination of Brilliant Blue FCF in some food samples using hydrophillic deep eutectic solvent-assisted magnetic nano gel-based dispersive solid phase microextraction prior to spectrophotometric analysis.: This innovative approach uses choline chloride in a deep eutectic solvent formulation to improve the detection of food dyes. The method promises greater efficiency and sensitivity, crucial for food safety and compliance (Erek et al., 2024).
Substrates
Choline acetyltransferase substrate
Disclaimer
For R&D or non-EU Food use. Not for retail sale.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Eutectic mixture of choline chloride/urea as a green solvent in synthesis of a coordination polymer:[Zn (O 3 PCH 2 CO 2)]? NH 4.
Liao JH, et al.
Inorganic Chemistry Communications, 8(4), 390-392 (2005)
Green and moisture-stable Lewis acidic ionic liquids (choline chloride.xZnCl2) catalyzed protection of carbonyls at room temperature under solvent-free conditions.
Duan Z, et al.
Catalysis Communications, 7, 651-656 (2006)
Andrew P Abbott et al.
Chemical communications (Cambridge, England), (1)(1), 70-71 (2003-03-04)
Eutectic mixtures of urea and a range of quaternary ammonium salts are liquid at ambient temperatures and have interesting solvent properties.
Determination of choline in milk, milk powder, and soy lecithin hydrolysates by flow injection analysis and amperometric detection with a choline oxidase based biosensor
Pati S, et al.
Journal of Agricultural and Food Chemistry, 52(15), 4638-4642 (2004)
Andrew P Abbott et al.
Physical chemistry chemical physics : PCCP, 11(21), 4269-4277 (2009-05-22)
Here we describe for the first time the electrolytic deposition of copper and copper composites from a solution of the metal chloride salt in either urea-choline chloride, or ethylene glycol-choline chloride based eutectics. We show that the deposition kinetics and
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