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C7527

Sigma-Aldrich

Choline chloride

BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98%

Synonym(s):

(2-Hydroxyethyl)trimethylammonium chloride

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About This Item

Linear Formula:
(CH3)3N(Cl)CH2CH2OH
CAS Number:
67-48-1
Molecular Weight:
139.62
Beilstein/REAXYS Number:
3563126
EC Number:
200-655-4
MDL number:
MFCD00011721
UNSPSC Code:
12352205
PubChem Substance ID:
24892968
NACRES:
NA.75

biological source

synthetic (organic)

Quality Level

300

product line

BioReagent

assay

≥98%

form

crystals

mol wt

Mw 139.62 g/mol

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

color

white

pH

5.0-6.5 (25 °C, 140 g/L)

mp

302-305 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

SMILES string

[Cl-].C[N+](C)(C)CCO

InChI

1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

InChI key

SGMZJAMFUVOLNK-UHFFFAOYSA-M

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General description

Choline chloride is a quaternary ammonium salt and associates with hydrogen bond donors (HBD). It is essential for the vital physiological functions and is used as a nutritional additive. Choline is a source of methyl groups for methyl-transfer reactions.

Application

Choline chloride has been used:
  • as a component of choline acetyltransferase (ChAT) buffer and for choline uptake in cultured human neuroblastoma (SK-N-SH) cells
  • for choline standard curve generation for quantifying phospholipase D (PLD) activity
  • as a component of slice solution for the dissection of entorhinal-hippocampal brain slices

Substrates

Choline acetyltransferase substrate

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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