Skip to Content
MilliporeSigma
All Photos(1)

Documents

46656

Supelco

Prednisolone

VETRANAL®, analytical standard

Synonym(s):

1,4-Pregnadiene-11β,17α,21-triol-3,20-dione, 1-Dehydrocortisol, 1-Dehydrohydrocortisone, 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C21H28O5
CAS Number:
50-24-8
Molecular Weight:
360.44
Beilstein/REAXYS Number:
1354103
EC Number:
200-021-7
MDL number:
MFCD00003649
UNSPSC Code:
41116107
PubChem Substance ID:
329756614
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

240 °C (dec.) (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1

InChI

1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key

OIGNJSKKLXVSLS-VWUMJDOOSA-N

Gene Information

human ... NR3C1(2908)

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Prednisolone is classified under the corticosteroids class of compounds.

Application

Prednisolone may be used as an analytical standard for the determination of prednisolone in:
  • Human plasma by multivariate curve resolution-alternating least squares (MCR-ALS) technique combined with high performance liquid chromatography-diode array detection (HPLC-DAD).
  • Urine, blood and food matrices by solid-phase extraction (SPE) and LC coupled to tandem mass spectrometry (LC-MS/MS).
  • Surface water samples by SPE and ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-QTOF) with electrospray ionization (ESI).
  • Bovine muscle samples by ESI-LC-MS/MS equipped with multiple reaction monitoring (MRM) detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360FD

Hazard Classifications

Repr. 1B

wgk_germany

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCBW5950
SZBD094XV
SZBA106XV
SZBA106X
SZE5207X

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 9

1 of 9

Dexamethasone VETRANAL®, analytical standard

Supelco

46165

Dexamethasone

Prednisone ≥98%

Sigma-Aldrich

P6254

Prednisone

vibrant-m

P2810000

Prednisolone sodium phosphate

Cinacalcet hydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML2012

Cinacalcet hydrochloride

Eprinomectin PESTANAL®, analytical standard, mixture of isomers

Supelco

32526

Eprinomectin

USP

USP

1557000

Prednisolone sodium phosphate

Flumethasone

Sigma-Aldrich

F9507

Flumethasone

Betamethasone VETRANAL®, analytical standard

Supelco

34166

Betamethasone

Atazanavir ≥98% (HPLC)

Sigma-Aldrich

SML1796

Atazanavir

Quantification of doping compounds in faecal samples from racing pigeons, by liquid chromatography-tandem mass spectrometry.
Moreira FX, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1089, 33-42 (2018)
Handling of highly coeluted chromatographic peaks by multivariate curve resolution for a complex bioanalytical problem: Quantitation of selected corticosteroids and mycophenolic acid in human plasma.
Rezaei F, et al.
Talanta, 187, 1-12 (2018)
Database-driven screening of South African surface water and the targeted detection of pharmaceuticals using liquid chromatography-High resolution mass spectrometry.
Wood TP, et al.
Environmental Pollution (Barking, Essex : 1987), 230, 453-462 (2017)
Ádám Tölgyesi et al.
Journal of pharmaceutical and biomedical analysis, 145, 805-813 (2017-08-20)
Veterinary drugs containing synthetic anabolic steroid and nitroimidazole active agents are not allowed for their applications in livestock of the European Union (EU). This paper presents analyses of twelve selected steroids and six nitroimidazole antibiotics at low levels (1.56μg/L-4.95μg/L and
Simultaneous determination of residues of non-steroidal anti-inflammatory drugs and glucocorticosteroids in animal muscle by liquid chromatography-tandem mass spectrometry.
Jedziniak P, et al.
Food Analytical Methods, 9(6), 1837-1848 (2016)
View All Related Papers

Protocols

HPLC Analysis of Prednisolone (Secondary Pharma Standard) on Ascentis® C18

Separation of Prednisolone, pharmaceutical secondary standard; traceable to USP, PhEur and BP

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service