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Dicloxacillin sodium salt hydrate

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C19H16Cl2N3NaO5S · xH2O
CAS Number:
Molecular Weight:
492.31 (anhydrous basis)
Beilstein/REAXYS Number:
4778711
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

[Na+].[H]O[H].Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C([O-])=O)-c4c(Cl)cccc4Cl

InChI

1S/C19H17Cl2N3O5S.Na.H2O/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1

InChI key

SIGZQNJITOWQEF-VICXVTCVSA-M

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General description

Chemical structure: ß-lactam
Dicloxacillins are mostly used β-lactam class of antibiotics that have major applications in veterinary medicines.

Application

Dicloxacillin sodium salt hydrate may be used as a reference standard for the determination of dicloxacillin sodium salt hydrate in:
  • Animal feed by pressurised liquid extraction (PLE) with liquid chromatography-quadrupole-linear ion-trap mass spectrometry (LC-QLIT-MS/MS) operating on multiple reaction monitoring mode (MRM).
  • Gilthead sea bream (Sparus aurata) by ultra-high pressure liquid chromatography (UHPLC) in conjunction with MS/MS.
  • Foodstuffs of animal origin and in milk by UHPLC-MS/MS equipped with electrospray ionisation (ESI).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Certificates of Analysis (COA)

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Development and validation of a pressurised liquid extraction liquid chromatography-electrospray-tandem mass spectrometry method for ?-lactams and sulfonamides in animal feed
Kantiani LF, et al.
Journal of Chromatography A, 1217(26), 4247-4254 (2010)
Multiresidue determination of veterinary drugs in aquaculture fish samples by ultra high performance liquid chromatography coupled to tandem mass spectrometry
Lopes RP, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 895(3), 39-47 (2012)
Determination of antibacterials in animal feed by pressurized liquid extraction followed by online purification and liquid chromatography-electrospray tandem mass spectrometry
Kantiani L, et al.
Analytical and Bioanalytical Chemistry, 398(3), 1195-1205 (2010)
Multiclass analysis of 23 veterinary drugs in milk by ultraperformance liquid chromatography-electrospray tandem mass spectrometry
Tang YY, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 881, 12-19 (2012)
High-throughput multiclass method for antibiotic residue analysis by liquid chromatography-tandem mass spectrometry
Chico J, et al.
Journal of Chromatography A, 1213(2), 189-199 (2008)

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