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USP

Piperacillin

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Piperacillin monohydrate

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About This Item

Empirical Formula (Hill Notation):
C23H27N5O7S · H2O
CAS Number:
66258-76-2
Molecular Weight:
535.57
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

piperacillin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

InChI

1S/C23H27N5O7S.H2O/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28;/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34);1H2/t13-,14-,15+,20-;/m1./s1

InChI key

NBXPLBPWMYNZTC-IDYPWDAWSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Piperacillin USP reference standard for use in specified quality tests and assays.Also used to prepare standard and system suitability solutions for the assay, and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Piperacillin Sodium
  • Piperacillin for Injection
  • Piperacillin
  • Piperacillin and Tazobactam for Injection

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317 - H412

Hazard Classifications

Aquatic Chronic 3 - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Piperacillin
United States Pharmacopeia, 45(5), 3562-3562 (2020)
Piperacillin and Tazobactam for Injection
United States Pharmacopeia, 39(3), 3567-3567 (2018)
Sangil Jeon et al.
Antimicrobial agents and chemotherapy, 58(7), 3744-3751 (2014-04-23)
Piperacillin in combination with tazobactam, a β-lactamase inhibitor, is a commonly used intravenous antibiotic for the empirical treatment of infection in intensive care patients, including burn patients. The purpose of this study was to develop a population pharmacokinetic (PK) model
Ashley W Sturm et al.
Pharmacotherapy, 34(1), 28-35 (2013-07-19)
To evaluate the steady-state pharmacokinetic and pharmacodynamic parameters of piperacillin in morbidly obese, surgical intensive care patients. Open-label single-center prospective study. Level I trauma center and university-affiliated teaching institution. Nine morbidly obese (body mass index [BMI] 40.0 kg/m² or higher)
Brian D VanScoy et al.
Antimicrobial agents and chemotherapy, 58(10), 6024-6031 (2014-07-30)
It is important to understand the relationship between antibiotic exposure and the selection of drug resistance in the context of therapy exposure. We sought to identify the ceftolozane-tazobactam exposure necessary to prevent the amplification of drug-resistant bacterial subpopulations in a
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