Skip to Content
Merck
All Photos(1)

Documents

92337

Sigma-Aldrich

Bromotrimethylsilane

purum, ≥97.0% (AT)

Synonym(s):

TMBS, Trimethylbromosilane, Trimethylsilyl bromide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(CH3)3SiBr
CAS Number:
2857-97-8
Molecular Weight:
153.09
Beilstein:
1731135
EC Number:
220-672-0
MDL number:
MFCD00000048
UNSPSC Code:
12352101
PubChem Substance ID:
329769891
NACRES:
NA.22

grade

purum

Quality Level

200

Assay

≥97.0% (AT)

form

liquid

contains

silver wool as stabilizer

refractive index

n20/D 1.424 (lit.)
n20/D 1.424

bp

79 °C (lit.)

density

1.16 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

C[Si](C)(C)Br

InChI

1S/C3H9BrSi/c1-5(2,3)4/h1-3H3

InChI key

IYYIVELXUANFED-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Bromotrimethylsilane is used with Cl3 to catalyze the direct allylation of a variety of alcohols with allyltrimethylsilane.

Application

Bromotrimethylsilane may be used as a derivatizing reagent for the determination of alkyl lysophospholipids in cell culture media using gas chromatography technique.

Other Notes

Powerful silylating agent ; Cleavage of ethers ; Smooth cleavage of phosphonic and phosphoric alkyl esters

Signal Word

Danger

Hazard Statements

H225,H314,H335,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH014

WGK

WGK 3

Flash Point(F)

10.4 °F

Flash Point(C)

-12 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
STBK6646
STBK8738
STBK0707
STBH6271
STBG6140V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 7

1 of 7

Phosphorus(V) oxybromide >95%

Sigma-Aldrich

376949

Phosphorus(V) oxybromide

2,6-Lutidine ReagentPlus®, 98%

Sigma-Aldrich

L3900

2,6-Lutidine

Diethyl phosphite 98%

Sigma-Aldrich

D99234

Diethyl phosphite

Thioanisole ReagentPlus®, ≥99%

Sigma-Aldrich

T28002

Thioanisole

N,O-Bis(trimethylsilyl)acetamide for GC derivatization, LiChropur™, ≥98.5% (GC)

Supelco

15269

N,O-Bis(trimethylsilyl)acetamide

Formamidine acetate salt 99%

Sigma-Aldrich

F15803

Formamidine acetate salt

Chlorotrimethylsilane ≥98.0% (GC)

Sigma-Aldrich

92361

Chlorotrimethylsilane

S. Hanessian et al.
Tetrahedron Letters, 25, 2515-2515 (1984)
J.L. Meek et al.
Journal of the American Chemical Society, 110, 2317-2317 (1988)
C. Flann et al.
Journal of the American Chemical Society, 109, 6097-6097 (1987)
J. Heberle et al.
Silylating Agents, 2nd ed. (1995)
J L Hughes et al.
Peptide research, 8(5), 298-300 (1995-09-01)
The cleavage of a peptide resin attached to a phenylacetomidomethyl (PAM) resin was investigated using bromotrimethylsilane (TMSBr) with thioanisole in trifluoroacetic acid (TFA), and by chlorotrimethylsilane (TMSCl) in the same reagents with lithium bromide. Both TMSBr and TMSCl cleaved the
View All Related Papers

Articles

Silylation of Non-Steroidal Anti-Inflammatory Drugs

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service