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MAB8292

Sigma-Aldrich

Anti-Parvovirus B19 Antibody, clone 521-5D

clone 521-5D, Chemicon®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

clone

521-5D, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable

isotype

IgG

shipped in

wet ice

Specificity

Human parvovirus B19. Recognizes amino acids 446-466 of VP2. Antibody inhibits haemagglutination.

Immunogen

B-19 virus purified from an acute serum specimen from a child with aplastic crisis (Anderson, 1986).

Application

Immunoassay.

Immunocytochemistry

Optimal working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
This Anti-Parvovirus B19 Antibody, clone 521-5D is validated for use in ELISA, IC, IH, IH(P) for the detection of Parvovirus B19.

Physical form

Format: Purified
Purified immunoglobulin. In 0.02M PB and 0.25M NaCl pH=7.6 with 0.1% NaN3 as a preservative.

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 12 months

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Human parvovirus B19 capsid antigen in granulocytes in parvovirus-B19-induced pancytopenia after bone marrow transplantation.
S Kobayashi, A Maruta, T Yamamoto, N Katayama, R Higuchi, Y Sakano, H Fujita et al.
Acta Haematologica null
Recombinant parvovirus B19 empty capsids inhibit fetal hematopoietic colony formation in vitro.
B Lindton, T Tolfvenstam, O Norbeck, L Markling, O Ringden, M Westgren, K Broliden
Fetal Diagnosis and Therapy null
Monitoring human parvovirus B19 virus-like particles and antibody complexes in solution by fluorescence correlation spectroscopy.
Jouni Toivola, Patrik O Michel, Leona Gilbert, Tomi Lahtinen, Varpu Marjomaki et al.
Biological Chemistry null
Peng Xu et al.
Antimicrobial agents and chemotherapy, 63(3) (2018-12-12)
Human parvovirus B19 (B19V), a member of the genus Erythroparvovirus of the family Parvoviridae, is a small nonenveloped virus that has a single-stranded DNA (ssDNA) genome of 5.6 kb with two inverted terminal repeats (ITRs). B19V infection often results in
Placental cellular immune response in women infected with human parvovirus B19 during pregnancy.
Jordan, JA; Huff, D; DeLoia, JA
Clinical and Diagnostic Laboratory Immunology null

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