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654019

Sigma-Aldrich

N-Boc-cis-4-hydroxy-L-proline

97%

Synonym(s):

N-Boc-cis-4-hydroxypyrrolidine-2-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C10H17NO5
CAS Number:
Molecular Weight:
231.25
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

solid

optical activity

[α]20/D -50.0±3°, c = 0.67 in methanol

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

146 °C (D) (lit.)

application(s)

peptide synthesis

SMILES string

CC(C)(C)OC(=O)N1C[C@@H](O)C[C@H]1C(O)=O

InChI

1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7-/m0/s1

InChI key

BENKAPCDIOILGV-BQBZGAKWSA-N

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Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Articles

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

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