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15544

Sigma-Aldrich

Boc-Hyp-OH

≥98.0% (TLC)

Synonym(s):

trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline, Boc-L-hydroxyproline

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About This Item

Empirical Formula (Hill Notation):
C10H17NO5
CAS Number:
Molecular Weight:
231.25
Beilstein:
4295484
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98.0% (TLC)

optical activity

[α]20/D −53.5±2°, c = 1% in DMF

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

123-127 °C (lit.)

application(s)

peptide synthesis

SMILES string

CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(O)=O

InChI

1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7+/m1/s1

InChI key

BENKAPCDIOILGV-RQJHMYQMSA-N

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WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

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