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Merck

PHR1280

Supelco

Xylit

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

Xylit

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

Lineare Formel:
HOCH2[CH(OH)]3CH2OH
CAS-Nummer:
Molekulargewicht:
152.15
Beilstein:
1720523
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to Ph. Eur. X0080000
traceable to USP 1720600

API-Familie

xylitol

Analysenzertifikat (CofA)

current certificate can be downloaded

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

94-97 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

OC[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4+,5+

InChIKey

HEBKCHPVOIAQTA-SCDXWVJYSA-N

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Allgemeine Beschreibung

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards. Xylitol is a naturally occurring polyhydric sugar alcohol with high sweetening power and anticariogenic properties.

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Xylitol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by capillary isotachophoresis.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC4431 in the slot below. This is an example certificate only and may not be the lot that you receive.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Sigma-Aldrich

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Sigma-Aldrich

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Separation and determination of sorbitol and xylitol in multi-component pharmaceutical formulations by capillary isotachophoresis
Pospisilova M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 17(3), 387-392 (1998)
The effect of xylitol on dental caries and oral flora
Nayak PA, et al.
Clinical, cosmetic and investigational dentistry, 6, 89-89 (2014)
Mette K Keller et al.
BMC oral health, 12, 44-44 (2012-10-25)
The increasing interest in probiotic lactobacilli in health maintenance has raised the question of potential risks. One possible side effect could be an increased acidogenicity in dental plaque. The aim of this study was to investigate the effect of probiotic
M C Ammons et al.
Biofouling, 29(4), 443-455 (2013-04-12)
Medically relevant biofilms have gained a significant level of interest, in part because of the epidemic rise in obesity and an aging population in the developed world. The associated comorbidities of chronic wounds such as pressure ulcers, venous leg ulcers
A V Ritter et al.
Journal of dental research, 92(6), 512-517 (2013-04-17)
The Xylitol for Adult Caries Trial was a three-year, double-blind, multi-center, randomized clinical trial that evaluated the effectiveness of xylitol vs. placebo lozenges in the prevention of dental caries in caries-active adults. The purpose of this secondary analysis was to

Protokolle

Separation of Maltotriose; Maltose; Xylitol

Separation of Ribose, United States Pharmacopeia (USP) Reference Standard; Xylitol, analytical standard; Mannose, United States Pharmacopeia (USP) Reference Standard

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