Direkt zum Inhalt
Merck

PHR1007

Supelco

D-Mannitol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

D-Mannitol, Mannite

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

Empirische Formel (Hill-System):
C6H14O6
CAS-Nummer:
Molekulargewicht:
182.17
Beilstein:
1721898
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
E-Nummer:
E421
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to Ph. Eur. M0200000
traceable to USP 1375105

API-Familie

mannitol

Analysenzertifikat (CofA)

current certificate can be downloaded

chemische Klasse(n) des Analyten

oligosaccharides

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

167-170 °C (lit.)

Anwendung(en)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChIKey

FBPFZTCFMRRESA-KVTDHHQDSA-N

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Allgemeine Beschreibung

Mannitol is an osmotic diuretic with a variety of clinical applications, one of which is the reduction of intracranial pressure. It is also found to be protective against ischemic and nephrotoxic acute renal failure.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

Mannitol may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using capillary isotachophoresis technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Ein Zuckeralkohol, der die Geschmacksknospen für süß anspricht. Wird für Untersuchungen zur Inhibition von Süße verwendet.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Ion Mobility: TWCCSN2 value of 132.3 Å2 [M-H]-

The collision cross section (CCS) measurement was provided by Waters Corporation, using the SYNAPT XS mass spectrometer.
For a description and overview of how ion mobility enables the measurement of the CCS of an ion visit ims.waters.com.
Further information on the SYNAPT XS mass spectrometer can be found on the IMS microsite and product webpage.

TWCCS measurements are expected to be within 2% of this reference value.

P/N PHR1007 is part of the Waters Extractables & Leachables UNIFI scientific library which can be downloaded from Waters Marketplace.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAB7668 in the slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Ähnliches Produkt

Produkt-Nr.
Beschreibung
Preisangaben

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Kunden haben sich ebenfalls angesehen

Slide 1 of 8

1 of 8

D-Mannitol meets EP, FCC, USP testing specifications

Sigma-Aldrich

M8429

D-Mannitol

D-Mannitol BioUltra, ≥99.0% (sum of enantiomers, HPLC)

Sigma-Aldrich

63559

D-Mannitol

D-Mannitol NIST® SRM® 920

NIST920

D-Mannitol

D-Mannitol ≥98% (GC), suitable for plant cell culture

Sigma-Aldrich

M1902

D-Mannitol

D-Mannitol tested according to Ph. Eur.

Sigma-Aldrich

17311

D-Mannitol

Fruktose Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1002

Fruktose

Xylit Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1280

Xylit

Sucralose Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1342

Sucralose

Mannitol-induced acute renal failure
RHD, et al.
Medicine, 69(3), 153-159 (1990)
Mannitol
Warren ES and Blantz CR
Archives of Internal Medicine, 141(4), 493-497 (1981)
Separation and determination of pharmaceutically important polyols in dosage forms by capillary isotachophoresis
Pospisilova M, et al.
Journal of Chromatography A, 772(1-2), 277-282 (1997)
Heikki O Koskela et al.
Chest, 124(6), 2171-2177 (2003-12-11)
To compare a new bronchial provocation test, the mannitol challenge, with cold air and histamine challenges to demonstrate airway hyperresponsiveness (AHR) in patients with difficult-to-diagnose asthma. A prospective study. Thirty-seven consecutive patients with recently diagnosed, steroid-naive, mild, or atypical asthma
Heikki O Koskela et al.
Chest, 125(6), 1985-1992 (2004-06-11)
To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma. A prospective study. University hospital. Thirty-seven steroid-naive, asthmatic subjects and 10 healthy subjects. The participants completed a symptom questionnaire, recorded

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.