PHR1041
Tetracyclin -hydrochlorid
Pharmaceutical Secondary Standard; Certified Reference Material
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)
About This Item
Empirische Formel (Hill-System):
C22H24N2O8 · HCl
CAS-Nummer:
Molekulargewicht:
480.90
Beilstein:
3844873
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
Empfohlene Produkte
Qualität
certified reference material
pharmaceutical secondary standard
Qualitätsniveau
Agentur
traceable to BP 480
traceable to Ph. Eur. T060000
traceable to USP 1651009
API-Familie
tetracycline
Analysenzertifikat (CofA)
current certificate can be downloaded
Methode(n)
HPLC: suitable
gas chromatography (GC): suitable
mp (Schmelzpunkt)
220-223 °C (lit.)
Anwendung(en)
pharmaceutical (small molecule)
Format
neat
Lagertemp.
2-8°C
SMILES String
Cl.CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O
InChI
1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChIKey
XMEVHPAGJVLHIG-FMZCEJRJSA-N
Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich
Allgemeine Beschreibung
Tetracycline hydrochloride is a broad-spectrum antibiotic, effective against both Gram-negative and Gram-positive microorganisms. Its aqueous solution has effective as a root canal irrigant for the removal of smear layer.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Anwendung
Tetracycline hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by kinetic spectrophotometric method.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem./physiol. Wirkung
Wirkungsweise: Inhibiert die Proteinsynthese (Elongation) durch Verhinderung des Bindens von Aminoacyl-tRNA an die 30S-Untereinheit.
Antimikrobielles Spektrum: Gram-negative und Gram-positive Bakterien.
Resistenzmechanismus: Verlust der Zellwandpermeabilität.
Antimikrobielles Spektrum: Gram-negative und Gram-positive Bakterien.
Resistenzmechanismus: Verlust der Zellwandpermeabilität.
Vorsicht
This product should be frozen below 0°C and protected from light and moisture. In these conditions, the product has been shown to retain activity for 4 years. Stock solutions should be stored at -20°C and are stable at 37°C for 4 days.
Angaben zur Herstellung
The product is freely soluble in water, soluble in methanol and ethanol but is insoluble in ether and hydrocarbons. In water, the product yields a clear, yellow-orange solution with heating and in 95% ethanol, 50 mg dissolved in 4 mL with heating yields a clear, yellow-green solution. Tetracycline is rapidly destroyed by alkali hydroxide solutions and standing water solutions become turbid due to hydrolysis and precipitation. The potency of tetracycline is reduced in solutions with pH below 2.
Hinweis zur Analyse
These secondary standards offer multi-traceability to the USP EP (PhEur) and BP primary standards where they are available.
Sonstige Hinweise
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Fußnote
To see an example of a Certificate of Analysis for this material enter LRAA7192 in the slot below. This is an example certificate only and may not be the lot that you receive.
Empfohlene Produkte
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Ähnliches Produkt
Produkt-Nr.
Beschreibung
Preisangaben
Signalwort
Warning
Gefahreneinstufungen
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Choose from one of the most recent versions:
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Kunden haben sich ebenfalls angesehen
Measurement and correlation of solubility of tetracycline hydrochloride in six organic solvents
Zhao Y and Wang Y
The Journal of Chemical Thermodynamics, 57(12), 9-13 (2013)
Kinetic spectrophotometric method for the determination of tetracycline hydrochloride in pharmaceutical formulations
Ahmida NHS, et al.
Archives of Applied Science Research, 1(12) (2009)
Tetracycline HCl solution as a root canal irrigant
Haznedaro?lu F and Ersev H
Journal of Endodontics, 27(12), 738-740 (2001)
T Bouchery et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 19(2), 131-140 (2013-02-13)
Symbiotic associations between eukaryotes and microorganisms are frequently observed in nature, and range along the continuum between parasitism and mutualism. The genus Wolbachia contains well-known intracellular bacteria of arthropods that induce several reproductive phenotypes that benefit the transmission of the
Leslie Cuthbertson et al.
Chemistry & biology, 20(2), 232-240 (2013-02-27)
The ligands that interact with the vast majority of small-molecule binding transcription factors are unknown, a significant gap in our understanding of sensory perception by cells. TetR-family regulators (TFRs) are found in most prokaryotes and are involved in regulating virtually
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
Setzen Sie sich mit dem technischen Dienst in Verbindung.