Direkt zum Inhalt
Merck
Alle Fotos(5)

Dokumente

T7660

Sigma-Aldrich

Tetracyclin -hydrochlorid

powder, BioReagent, suitable for cell culture

Synonym(e):

Tetracycline HCL

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(5)

About This Item

Empirische Formel (Hill-System):
C22H24N2O8 · HCl
CAS-Nummer:
64-75-5
Molekulargewicht:
480.90
Beilstein:
3844873
EG-Nummer:
200-593-8
MDL-Nummer:
MFCD00078142
UNSPSC-Code:
51101500
PubChem Substanz-ID:
24900468

Produktlinie

BioReagent

Qualitätsniveau

200

Form

powder

Lagerbedingungen

(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)

Methode(n)

cell culture | mammalian: suitable

Verunreinigungen

endotoxin, tested

Inchi Code

1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,13-15,25,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,13?,14?,15-,21+,22-;/m0./s1

Farbe

yellow

InChIKey

JCBQYRBTRRPKMO-PMMNLZCOSA-N
XMEVHPAGJVLHIG-FMZCEJRJSA-N

mp (Schmelzpunkt)

220-223 °C (lit.)

Wirkungsspektrum von Antibiotika

Gram-negative bacteria
Gram-positive bacteria

Wirkungsweise

protein synthesis | interferes

Lagertemp.

−20°C

SMILES String

Cl.CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O

InChI

1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Verwandte Kategorien

Allgemeine Beschreibung

Chemical structure: tetracycline

Anwendung

Tetracycline is a broad spectrum polyketide antibiotic with clinical uses in treating bacterial infections such as Rocky Mountain spotted fever, typush fever, tick fevers, Q fever, and Brill-Zinsser disease and to treat upper respiratory infections and acne. It has been used in studies of multidrug resistance and potential side effects including acute pancreatitis. It is recommended for use in cell culture applications at 10 mg/L.

Biochem./physiol. Wirkung

Wirkungsweise: Inhibiert die Proteinsynthese (Elongation) durch Verhinderung des Bindens von Aminoacyl-tRNA an die 30S-Untereinheit.

Antimikrobielles Spektrum: Gram-negative und Gram-positive Bakterien.

Resistenzmechanismus: Verlust der Zellwandpermeabilität.

Vorsicht

This product should be frozen below 0°C and protected from light and moisture. In these conditions, the product has been shown to retain activity for 4 years. Stock solutions should be stored at -20°C and are stable at 37°C for 4 days.

Angaben zur Herstellung

The product is freely soluble in water, slightly soluble in 96% ethanol, and is practically insoluble in acetone. Tetracycline is rapidly destroyed by alkali hydroxide solutions and standing water solutions become turbid due to hydrolysis and precipitation. The potency of tetracycline is reduced in solutions with pH below 2.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place

Signalwort

Warning

Gefahreneinstufungen

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Kunden haben sich ebenfalls angesehen

Slide 1 of 3

1 of 3

Kanamycin -sulfat aus Streptomyces kanamyceticus powder, BioReagent, suitable for cell culture, suitable for plant cell culture

Sigma-Aldrich

K1377

Kanamycin -sulfat aus Streptomyces kanamyceticus

Gentamicin -sulfat (Salz) powder, BioReagent, suitable for cell culture

Sigma-Aldrich

G1264

Gentamicin -sulfat (Salz)

Bluo-Gal reagent for selection of recombinant bacterial clones

Sigma-Aldrich

B2904

Bluo-Gal

Silvia Emma Rossi et al.
Nature communications, 9(1), 4830-4830 (2018-11-18)
Dna2 is a DNA helicase-endonuclease mediating DSB resection and Okazaki fragment processing. Dna2 ablation is lethal and rescued by inactivation of Pif1, a helicase assisting Okazaki fragment maturation, Pol32, a DNA polymerase δ subunit, and Rad9, a DNA damage response
Derek F Ceccarelli et al.
Structure (London, England : 1993), 27(6), 1000-1012 (2019-05-06)
Pseudoenzymes have been identified across a diverse range of enzyme classes and fulfill important cellular functions. Examples of pseudoenzymes exist within ubiquitin conjugating and deubiquitinase (DUB) protein families. Here we characterize FAM105A/OTULINL, the only putative pseudodeubiquitinase of the ovarian tumor protease
Marta Lukačišinová et al.
Nature communications, 11(1), 3105-3105 (2020-06-21)
Genetic perturbations that affect bacterial resistance to antibiotics have been characterized genome-wide, but how do such perturbations interact with subsequent evolutionary adaptation to the drug? Here, we show that strong epistasis between resistance mutations and systematically identified genes can be
Yasuhiro Igarashi et al.
Journal of natural products, 74(4), 670-674 (2011-03-11)
A new spirotetronate-class polyketide, maklamicin (1), was isolated from the culture extract of an endophytic actinomycete of the genus Micromonospora. The structure and relative configuration of 1 were elucidated by interpretation of NMR and other spectroscopic data, and the absolute
Leslie Cuthbertson et al.
Chemistry & biology, 20(2), 232-240 (2013-02-27)
The ligands that interact with the vast majority of small-molecule binding transcription factors are unknown, a significant gap in our understanding of sensory perception by cells. TetR-family regulators (TFRs) are found in most prokaryotes and are involved in regulating virtually
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.