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Merck

A5882

Supelco

Antipyrin

analytical standard

Synonym(e):

2,3-Dimethyl-1-phenyl-3-pyrazolin-5-on, Phenazon

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About This Item

Empirische Formel (Hill-System):
C11H12N2O
CAS-Nummer:
Molekulargewicht:
188.23
Beilstein:
157775
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:

Qualität

analytical standard

Qualitätsniveau

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

109-111 °C (lit.)

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

SMILES String

CN1N(C(=O)C=C1C)c2ccccc2

InChI

1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3

InChIKey

VEQOALNAAJBPNY-UHFFFAOYSA-N

Angaben zum Gen

human ... PTGS1(5742)

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Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

Antipyrine may be used as:
  • Pharmaceutical reference standard for the determination of the analyte in animal plasma and serum by various chromatography techniques.
  • Internal standard for the analysis of creatinine and uric acid in human plasma by micellar electrokinetic chromatography.
  • Reference standard to investigate the effect of diseases, pharmaceuticals, and environmental factors on hepatic oxidative metabolism activity in humans and animals in vivo, owing to its physicochemical, biochemical, and pharmacokinetic properties.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Analysenzertifikate (COA)

Lot/Batch Number

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Nicotinamid ≥98.5% (HPLC)

Sigma-Aldrich

72345

Nicotinamid

Meglumine diatrizoate organic

Sigma-Aldrich

M5266

Meglumine diatrizoate

High-pressure liquid chromatographic analysis of antipyrine in small plasma samples
Shargel L, et al.
Journal of Pharmaceutical Sciences, 68(8), 1052-1054 (1979)
Rapid determination of drugs in biofluids by capillary electrophoresis Measurement of antipyrine in saliva for pharmacokinetic studies
Perrett D and Ross GA
Journal of Chromatography A, 700(1-2), 179-186 (1995)
Automated high-performance liquid chromatographic determination of antipyrine and its main metabolites in plasma, saliva and urine, including 4, 4?-dihydroxy-antipyrine
Teunissen MWE, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 278(3), 367-378 (1983)
Simultaneous determination of creatinine and uric acid in human plasma and urine by micellar electrokinetic chromatography
Miyake M, et al.
Journal of High Resolution Chromatography, 14(3), 181-185 (1991)
Antipyrine, indocyanine green, and lorazepam determined in plasma by high-pressure liquid chromatography.
Awni WM and Bakker LJ
Clinical Chemistry, 35(10), 2124-2126 (1989)

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