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01518

Supelco

Ginsenosid Rd

analytical standard

Synonym(e):

(3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl-2-O-β-D-glucopyranosyl-β-D-glucopyranosid, Gypenosid VIII

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About This Item

Empirische Formel (Hill-System):
C48H82O18
CAS-Nummer:
52705-93-8
Molekulargewicht:
947.15
EG-Nummer:
258-118-5
UNSPSC-Code:
85151701
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

100

Assay

≥95.0% (HPLC)

Haltbarkeit

limited shelf life, expiry date on the label

Anwendung(en)

food and beverages

Format

neat

Lagertemp.

2-8°C

SMILES String

C\C(C)=C/CC[C@](C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H]2CC[C@]3(C)[C@@H]2[C@H](O)C[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C(C)(C)[C@@H]5CC[C@@]34C

InChI

1S/C48H82O18/c1-21(2)15-22(3)17-48(8,66-43-40(60)37(57)34(54)28(19-50)62-43)24-11-13-47(7)23-9-10-30-45(4,5)31(12-14-46(30,6)25(23)16-26(52)32(24)47)64-44-41(38(58)35(55)29(20-51)63-44)65-42-39(59)36(56)33(53)27(18-49)61-42/h15,22-44,49-60H,9-14,16-20H2,1-8H3/t22?,23?,24-,25?,26-,27+,28+,29+,30?,31?,32+,33+,34+,35+,36-,37-,38-,39+,40+,41+,42-,43-,44-,46+,47+,48-/m0/s1

InChIKey

IRBVCFDYIGGFFY-ADSMOORZSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Ginsenoside is a steroid-like molecular component having gonane steroid nucleus along with different sugar moieties attached to them found in the roots of Panax ginseng. Ginsenoside Rd is the main active component of ginsenosides, having the ability to inhibit Ca2+ influx through receptors and store-operated Ca2+ channel. From neural stem cells, it is seen to enhance astrocyte differentiation. It also reduces the 3-nitropropionic acid-induced motor impairment and cell loss in stratum. It constitutes to one of the major ingredient in total saponin content from Panax notoginseng.

Anwendung

It was used as reference standard in UPLC/TOF-MS analysis of human plasma to determine Ginsenoside metabolites.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
BCCD3913
BCCB9725
BCBZ5126
BCBT6662
BCBS0665V

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Ginsenosid Rg3 ≥98% (HPLC)

Sigma-Aldrich

SML0184

Ginsenosid Rg3

Ginsenosid Rg1 primary reference standard

00370580

Ginsenosid Rg1

Ginsenoside-Rc from Panax ginseng (Korean ginseng) root triterpenoid saponin, ≥98% (HPLC)

Sigma-Aldrich

G0902

Ginsenoside-Rc from Panax ginseng (Korean ginseng) root

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Supelco

64139

Ginsenosid Rg3

Ginsenosid Rh2 analytical standard

Supelco

73658

Ginsenosid Rh2

Ginsenosid Rg5 analytical standard

Supelco

43016

Ginsenosid Rg5

Ginsenoside-Rb1 from Panax ginseng (Korean ginseng) root ≥98% (HPLC), triterpenoid saponin

Sigma-Aldrich

G0777

Ginsenoside-Rb1 from Panax ginseng (Korean ginseng) root

Gypenosid XVII phyproof® Reference Substance

PHL83506

Gypenosid XVII

Ginsenosid Rf primary reference standard

01580590

Ginsenosid Rf

Li Wang et al.
The Journal of surgical research, 176(1), 267-274 (2011-08-30)
Organ transplantation is a life-saving procedure for patients with organ failure. However, the side effects of long-term application of classic immunosuppressant remain major obstacles for successful transplantation. Therefore, new and safe immunosuppressive drugs against acute and chronic rejection are eagerly
Ruidong Ye et al.
Neurochemistry international, 58(3), 391-398 (2010-12-28)
We previously found that ginsenoside Rd (Rd), one of the main active ingredients in Panax ginseng, attenuates neuronal oxidative damage in vitro induced by hydrogen peroxide and oxygen-glucose deprivation. In this study, we sought to investigate the potential protective effects
R Ye et al.
Neuroscience, 178, 169-180 (2011-01-12)
We previously found that ginsenoside Rd (Rd), one of the major active ingredients in Panax ginseng, protects neuronal cells from hydrogen peroxide and oxygen-glucose deprivation, an in vitro model of cerebral ischemia. In this study, we examined the protective effects
Dong Sun et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(3-4), 369-373 (2011-09-09)
Ginsenoside-Rd (GS-Rd) is one of the major active components of Panax ginseng, and was shown to have the protective effects against several insults. However, we still lack some basic knowledge of GS-Rd, including its pharmacokinetic, tissue distribution and excretion in
Do Yeon Kim et al.
Fitoterapia, 83(1), 215-222 (2011-11-09)
As part of our search for biologically active anti-osteoporotic agents that enhance the differentiation and mineralization of osteoblastic MC3T3-E1 cells, we identified the ginsenoside Rd as the most active compound among ginsenosides. In this study, we showed that Rd stimulates
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Artikel

Ginsenosides

Ginsenosides Separation in Ginseng. The HPLC method was first optimized using a ginsenoside standard mixture, and was then applied to a sample of American Ginseng root.

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