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00370580

Ginsenosid Rg1

primary reference standard

Synonym(e):

(3β,6α,12β)-3,12-Dihydroxydammar-24-en-6,20-diyl-bis-β-D-glucopyranosid, Ginsenosid A2, Ginsenosid g1, Panaxosid A, Panaxosid Rg1, Sanchinosid C1, Sanchinosid Rg1

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About This Item

Empirische Formel (Hill-System):
C42H72O14
CAS-Nummer:
22427-39-0
Molekulargewicht:
801.01
EG-Nummer:
244-989-9
MDL-Nummer:
MFCD00210293
UNSPSC-Code:
85151701
PubChem Substanz-ID:
329747051
NACRES:
NA.24

Qualität

primary reference standard

Haltbarkeit

limited shelf life, expiry date on the label

Hersteller/Markenname

HWI

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

C\C(C)=C/CC[C@](C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H]2CC[C@]3(C)[C@@H]2[C@H](O)C[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5[C@H](C[C@@]34C)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O

InChI

1S/C42H72O14/c1-20(2)10-9-13-42(8,56-37-34(52)32(50)30(48)25(19-44)55-37)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36+,37-,39+,40+,41+,42-/m0/s1

InChIKey

YURJSTAIMNSZAE-HHNZYBFYSA-N

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Allgemeine Beschreibung

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Anwendung

Referenzstandard für die Analyse von pflanzlichen Medizinprodukten.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
HWI03094-1
HWI03094
HWI02086-2
HWI02086-1
HWI02086

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Ginsenoside-Rb1 from Panax ginseng (Korean ginseng) root ≥98% (HPLC), triterpenoid saponin

Sigma-Aldrich

G0777

Ginsenoside-Rb1 from Panax ginseng (Korean ginseng) root

Ginsenosid Re analytical standard

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Ginsenosid Rg2 analytical standard

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08171

Ginsenosid Rg2

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Ginsenosid Rf analytical standard

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65839

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Ginsenosid Rh1 analytical standard

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56805

Ginsenosid Rh1

Wei Li et al.
Brain research bulletin, 88(5), 501-506 (2012-05-24)
Excessive accumulation of amyloid-β (Aβ) has been proposed as a pivotal event in Alzheimer's disease (AD) pathogenesis. Possible mechanisms underlying Aβ-induced neurotoxicity include inflammation and apoptosis. Here, the protective effect of ginsenoside Rg1 (GRg1) on neuronal damage was examined in
QianKun Quan et al.
PloS one, 8(3), e59155-e59155 (2013-03-23)
The present study was designed to examine the effects of ginsenoside Rg1 on expression of peroxisome proliferator-activated receptor γ (PPARγ) and insulin-degrading enzyme (IDE) in the hippocampus of rat model of Alzheimer's disease (AD) to determine how ginsenoside Rg1 (Rg1)
Wei Li et al.
Life sciences, 91(15-16), 809-815 (2012-09-18)
In the present study we aimed to investigate the neuroprotective effect of ginsenoside Rg1 (GRg1) on neuronal damage examined in an adopted in vitro inflammatory neurodegeneration model and the involvement of p38 MAPK signal pathway. The supernatant from Aβ(1-40)-stimulated THP-1
Jiaying Wu et al.
Neurochemistry international, 62(1), 92-102 (2012-10-16)
Ginsenoside Rg1, a steroidal saponin of high abundance in ginseng, possesses the neuroprotective effects. In this study, we tried to explore the effect of Rg1 on promoting differentiation of mouse embryonic stem (ES) cells towards the neuronal lineage and its
Y Takino
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 114(8), 550-564 (1994-08-01)
The pharmacodynamics of ginsenoside-Rg1 (Rg1), -Rb1 (Rb1) and -Rb2 (Rb2) in rats were studied. In these studies, obvious differences were found in their pharmacodynamics. That is, Rg1 was easily hydrated to the same prospogenins in both rat stomach and 0.1
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