Direkt zum Inhalt
Merck
Alle Fotos(1)

Dokumente

LM1902

Avanti

17:0-20:4 PI(5)P

Avanti Polar Lipids LM1902, powder

Synonym(e):

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-5′-phosphate) (ammonium salt)

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)

About This Item

Empirische Formel (Hill-System):
C46H88N2O16P2
CAS-Nummer:
1246304-69-7
Molekulargewicht:
987.14
UNSPSC-Code:
12352211
NACRES:
NA.25

Form

powder

Hersteller/Markenname

Avanti Polar Lipids LM1902

Verpackung

1 ea of 1 × (with stopper and crimp cap (LM1902-1EA))

Anwendung(en)

lipidomics
metabolomics

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]

Verwandte Kategorien

Allgemeine Beschreibung

Phosphatidylinositol 5-Phosphate (PI5P) is present in the endosomes, trans-Golgi network and smooth endoplasmic reticulum. It is abundantly localized to the plasma membrane but also found in the intracellular membranes of the organelles.

Biochem./physiol. Wirkung

Phosphorylation of phosphatidylinositol 5-phosphate (PI5P) by phosphatidylinositol 5-phosphate (PI5P) type II PIPKs (PIPKIIs) produces phosphatidylinositol 4,5-bisphosphate (PI-4,5-P2), which, is a potent signaling molecule. PI5P is a lipid messenger associated with stress-induced pathways in the nucleus. It is known to possess housekeeping functions and aids in cell activation during bacterial infections.

Verpackung

2 mL Amber Serum Vial with Stopper and Crimp Cap (LM1902-1EA)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Amber J McCartney et al.
BioEssays : news and reviews in molecular, cellular and developmental biology, 36(1), 52-64 (2013-12-11)
Recent studies of the low abundant signaling lipid, phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2 ), reveal an intriguingly diverse list of downstream pathways, the intertwined relationship between PI(3,5)P2 and PI5P, as well as links to neurodegenerative diseases. Derived from the structural lipid phosphatidylinositol
Natsuko Jin et al.
Biochemical Society transactions, 44(1), 177-184 (2016-02-11)
Phosphorylated phosphatidylinositol lipids are crucial for most eukaryotes and have diverse cellular functions. The low-abundance signalling lipid phosphatidylinositol 3,5-bisphosphate [PI(3,5)P2] is critical for cellular homoeostasis and adaptation to stimuli. A large complex of proteins that includes the lipid kinase Fab1-PIKfyve
Matthew W Bunce et al.
The Journal of biological chemistry, 283(13), 8678-8686 (2008-01-26)
Phosphoinositide signaling pathways regulate numerous processes in eukaryotic cells, including migration, proliferation, and survival. The regulatory lipid phosphatidylinositol 4,5-bisphosphate is synthesized by two distinct classes of phosphatidylinositol phosphate kinases (PIPKs), the type I and II PIPKs. Although numerous physiological functions

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.