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Merck

W266507

Sigma-Aldrich

DL-Menthol

≥95%, FCC, FG

Synonym(e):

Menthol, 2-Isopropyl-5-methyl-cyclohexanol, Hexahydrothymol

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About This Item

Empirische Formel (Hill-System):
C10H20O
CAS-Nummer:
Molekulargewicht:
156.27
FEMA-Nummer:
2665
Beilstein:
3194263
EG-Nummer:
CoE-Nummer:
63
MDL-Nummer:
UNSPSC-Code:
12164502
PubChem Substanz-ID:
Flavis-Nummer:
2.015
NACRES:
NA.21

Biologische Quelle

synthetic

Qualitätsniveau

Qualität

FG
Halal
Kosher

Einhaltung gesetzlicher Vorschriften

EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 172.515

Dampfdruck

0.8 mmHg ( 20 °C)

Assay

≥95%

bp

216 °C (lit.)

mp (Schmelzpunkt)

34-36 °C (lit.)

Dichte

0.89 g/mL at 25 °C (lit.)

Anwendung(en)

flavors and fragrances

Dokumentation

see Safety & Documentation for available documents

Nahrungsmittelallergen

no known allergens

Organoleptisch

woody; minty; cooling

SMILES String

CC(C)C1CCC(C)CC1O

InChI

1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3

InChIKey

NOOLISFMXDJSKH-UHFFFAOYSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

DL-Menthol is a racemic mixture of D- and L-menthol. Its optical resolution produces L-menthol, which is widely used in confectionaries cosmetics and toothpaste for its characteristic peppermint flavor and cooling effect.

Anwendung


  • Developing of an eco-friendly liquid-liquid microextraction method by using menthol-based hydrophobic deep eutectic solvent for determination of basic fuchsin dye: assessment of the greenness profile.: This study introduces a sustainable method using DL-menthol-based solvents for extracting and analyzing industrial dyes, providing a green alternative to traditional solvent extraction techniques (Aydin et al., 2024).

  • Potential fumigant toxicity of essential oils against Sitotroga cerealella (Olivier) (Lepidoptera: Gelechiidae) and its egg parasitoid Trichogramma evanescens (Hymenoptera: Trichogrammatidae).: This research highlights the efficacy of DL-menthol in pest management, examining its potential as a natural fumigant that could replace synthetic chemicals in agricultural practices (Elbehery et al., 2024).

  • Differential analysis of volatiles in five types of mosquito-repellent products by chemometrics combined with headspace GC-Orbitrap HRMS nontargeted detection.: Explores the application of DL-menthol in developing mosquito-repellent formulations, enhancing the understanding of volatile compounds in public health products (Zhao et al., 2024).

  • Vortex-assisted dispersive liquid-liquid microextraction based on the hydrophobic deep eutectic solvent-based ferrofluid for extraction and detection of myclobutanil.: Utilizes DL-menthol in innovative extraction methods for pesticide analysis, promoting safer and more efficient detection techniques in food safety and environmental monitoring (Fattahi et al., 2023).

Biochem./physiol. Wirkung

Taste at 25 ppm

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 1

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


Analysenzertifikate (COA)

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(-)-Menthol for synthesis

Sigma-Aldrich

8.14113

(-)-Menthol

Menthol United States Pharmacopeia (USP) Reference Standard

USP

1381709

Menthol

Salicylsäure-menthylester mixture of isomers

Sigma-Aldrich

84320

Salicylsäure-menthylester

vibrant-m

Y0001126

Lavendel-Spiköl aus Lavandula spica

Thymol FCC, FG

Sigma-Aldrich

W306606

Thymol

(1S,2S,5R)-(+)-Neomenthol ≥95%

Sigma-Aldrich

235180

(1S,2S,5R)-(+)-Neomenthol

Methylsalicylat ≥98%, FCC, FG

Sigma-Aldrich

W274518

Methylsalicylat

Lucie Percevault et al.
The journal of physical chemistry. B, 124(41), 9126-9135 (2020-09-19)
We have performed small-angle neutron scattering in a momentum transfer range (0.05 < Q < 0.5 Å-1) to study long-range order and concentration fluctuations in deep eutectic solvents (DESs) and their aqueous solutions. Ethaline (choline chloride/ethylene glycol), glycerol/lactic acid, and
Optimized synthesis of lipase-catalyzed l-menthyl butyrate by Candia rugosa lipase.
Shih L, et al.
Food Chemistry, 100(3), 1223-1228 (2007)
Joanne D'Silva et al.
American journal of preventive medicine, 43(5 Suppl 3), S242-S248 (2012-10-25)
Menthol cigarettes account for 25% of the market in the U.S. The Food and Drug Administration currently is considering regulatory action on tobacco products, including a ban on menthol cigarettes. With 39% of menthol smokers reporting that they would quit
Shengyi Lu et al.
European journal of oral sciences, 121(1), 29-35 (2013-01-22)
This study was designed to investigate the effect of surrogate orofacial pain models on the quantitative sensory testing (QST) profile in healthy participants. Capsaicin, menthol, or saline (control) were applied topically onto the gingiva of 15 healthy subjects for 15 min.
Abrar Ashoor et al.
The Journal of pharmacology and experimental therapeutics, 347(2), 398-409 (2013-08-24)
The effects of alcohol monoterpene menthol, a major active ingredient of the peppermint plant, were tested on the function of human 5-hydroxytryptamine type 3 (5-HT3) receptors expressed in Xenopus laevis oocytes. 5-HT (1 μM)-evoked currents recorded by two-electrode voltage-clamp technique

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