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149837

Sigma-Aldrich

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydrochinolin

≥99%

Synonym(e):

1,2-Dihydro-2-ethoxychinolin-1-carbonsäure-ethylester, N-Ethoxycarbonyl-2-ethoxy-1,2-dihydrochinolin, EEDQ

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About This Item

Empirische Formel (Hill-System):
C14H17NO3
CAS-Nummer:
16357-59-8
Molekulargewicht:
247.29
Beilstein:
533048
EG-Nummer:
240-418-2
MDL-Nummer:
MFCD00006703
UNSPSC-Code:
12352005
PubChem Substanz-ID:
24848976
NACRES:
NA.22

Qualitätsniveau

200

Assay

≥99%

Form

solid

Eignung der Reaktion

reaction type: Coupling Reactions

mp (Schmelzpunkt)

62-67 °C (lit.)

Anwendung(en)

peptide synthesis

Lagertemp.

2-8°C

SMILES String

CCOC1C=Cc2ccccc2N1C(=O)OCC

InChI

1S/C14H17NO3/c1-3-17-13-10-9-11-7-5-6-8-12(11)15(13)14(16)18-4-2/h5-10,13H,3-4H2,1-2H3

InChIKey

GKQLYSROISKDLL-UHFFFAOYSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline(EEDQ) is a stable, and readily available reagent used to prepare amides and peptides in high yields. At ambient temperature, EEDQ is soluble in an aqueous medium containing organic solvents but insoluble in water. It is used as a coupling agent in peptide synthesis.

Anwendung

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline is used as a coupling agent:
  • In the regioselective quaternization of chitosan and its amphiphilic derivatives.
  • In the preparation of amide-type S-MA derivative-modified QCM sensors.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Sigma-Aldrich

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Bromessigsäure

H Gozlan et al.
Neuropharmacology, 33(3-4), 423-431 (1994-03-01)
The effects of N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ), an alkylating agent producing irreversible blockade of various membrane bound receptors in brain, were investigated on four different types of serotonin receptors, 5-HT1A, 5-HT1B, 5-HT2A and 5-HT3, in various brain regions in the rat. In
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Protokolle

cAMP Assays

cAMP measurements are obtained using an ELISA assay (Harlow and Lane 1988). Commercial radio-immunoassays, or ELISA kits, to assay cAMP can be purchased from various manufacturers.

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