SML1322
Ipamorelin acetate
≥98%
Synonym(s):
2-Methylalanyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-D-phenylalanyl-L-lysinamide acetate, Aib-His-D-2-Nal-D-Phe-Lys-NH2 acetate, NNC 26-0161 acetate;
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About This Item
Empirical Formula (Hill Notation):
C38H49N9O5 · xC2H4O2
CAS Number:
Molecular Weight:
711.85 (free base basis)
UNSPSC Code:
51111800
NACRES:
NA.77
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Quality Level
assay
≥98%
form
powder
color
white to beige
solubility
H2O: 20 mg/L, clear
shipped in
wet ice
storage temp.
−20°C
Biochem/physiol Actions
Ipamorelin is a selective growth hormone secretagogue and agonist of the ghrelin receptor that selectively stimulates the ghrelin receptor and causes growth hormone release. The potency and efficacy of ipamorelin are similar to GHRP-6 but without increase plasma levels of ACTH or cortisol. Ipamorelin appears to enter the central nervous system and to activate GRLN receptors in the spinal cord.
Ipamorelin is known to be useful in reducing the symptoms of postoperative ileus is a gastrointestinal dysfunction arising due to abdominal surgery. Symptoms include abdominal distention, vomiting, nausea, constipation and anorexia.
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Kalina Venkova et al.
The Journal of pharmacology and experimental therapeutics, 329(3), 1110-1116 (2009-03-18)
Ghrelin and ghrelin mimetics stimulate appetite and enhance gastric motility. The present study investigates whether ipamorelin, a selective growth hormone secretagogue and agonist of the ghrelin receptor, would accelerate gastrointestinal transit and ameliorate the symptoms in a rodent model of
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