Skip to Content
MilliporeSigma
All Photos(1)

Documents

SML0669

Sigma-Aldrich

VUF11207 trifluoroacetate salt

≥98% (HPLC)

Synonym(s):

(E)-N-(3-(2-Fluorophenyl)-2-methylallyl)-3,4,5-trimethoxy-N-(2-(1-methylpyrrolidin-2-yl)ethyl)benzamide trifluoroacetate salt, N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-benzamide trifluoroacetate salt

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C27H35FN2O4 · C2HF3O2
CAS Number:
1378524-41-4
Molecular Weight:
584.60
MDL number:
MFCD26961112
UNSPSC Code:
51111800
PubChem Substance ID:
329825579
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

storage condition

desiccated
protect from light

color

white to beige

solubility

H2O: 5 mg/mL, clear (warmed)

storage temp.

−20°C

SMILES string

O=C(N(CCC1N(C)CCC1)C/C(C)=C/C2=C(F)C=CC=C2)C3=CC(OC)=C(OC)C(OC)=C3.OC(C(F)(F)F)=O

InChI

1S/C27H35FN2O4.C2HF3O2/c1-19(15-20-9-6-7-11-23(20)28)18-30(14-12-22-10-8-13-29(22)2)27(31)21-16-24(32-3)26(34-5)25(17-21)33-4;3-2(4,5)1(6)7/h6-7,9,11,15-17,22H,8,10,12-14,18H2,1-5H3;(H,6,7)/b19-15+;

InChI key

GZXNWMFPSYCITC-QTCZRQAZSA-N

Biochem/physiol Actions

VUF11207 is a highly potent CXCR7 agonist. VUF11207 induces recruitment of β-arrestin2 to the CXCR7 followed by internalization of the receptor.
VUF11207 is considered as a selective inhibitor of CXCR4 (C-X-C motif chemokine receptor 4).

Other Notes

Hygroscopic and light sensitive

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Breast Cancer: An Examination of the Potential of ACKR3 to Modify the Response of CXCR4 to CXCL12
del Molino del Barrio I, et al.
International Journal of Molecular Sciences, 19(11), 3592-3592 (2018)

Articles

Chemokine Receptors

We offer many products related to chemokine receptors for your research needs.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service