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SAB5500109

Sigma-Aldrich

Anti-FOXP3 antibody, Rabbit monoclonal

clone SP97, recombinant, expressed in proprietary host, affinity isolated antibody

Synonym(s):

Anti-AIID, Anti-DIETER, Anti-IPEX, Anti-JM2, Anti-PIDX, Anti-XPID

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

recombinant

expressed in proprietary host

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

SP97, monoclonal

species reactivity

human (tested)

species reactivity (predicted by homology)

dog, mouse, bovine, pig, rat

technique(s)

immunohistochemistry: 1:100

isotype

IgG

UniProt accession no.

Q9BZS1

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... FOXP3(50943)

General description

FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at a low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.

Immunogen

Synthetic peptide corresponding to C-terminus of human FOXP3 protein.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Certificates of Analysis (COA)

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