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SAB5200032

Sigma-Aldrich

Monoclonal Anti-TRPM7 antibody produced in mouse

clone S74-25, 1 mg/mL, purified immunoglobulin

Synonym(s):

Anti-CHAK, Anti-CHAK1, Anti-Channel kinase 1, Anti-LTRPC7, Anti-TRP PLIK, Anti-TRPM7, S74-25

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

S74-25, monoclonal

form

buffered aqueous glycerol solution

mol wt

antigen predicted mol wt 220 kDa

species reactivity

mouse, rat, human

concentration

1 mg/mL

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NP_001157797.1

UniProt accession no.

Q96QT4

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

mouse ... Trpm7(58800)

Specificity

Detects ~220 kDa. No cross-reactivity against TrpM6

Immunogen

Fusion protein amino acids 1817-1863 (C- terminus) of mouse TrpM7, Accession Number Q923J1

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fei Yang et al.
Oxidative medicine and cellular longevity, 2020, 6724810-6724810 (2020-03-28)
Transient receptor potential melastatin subfamily member 7 (TRPM7) was essential in the growth and metastatic ability of prostate cancer cells. However, the effects and the relevant molecular mechanisms of TRPM7 on metastasis of prostate cancer under hypoxic atmosphere remain unclear.
Jing Wang et al.
Asian Pacific journal of cancer prevention : APJCP, 15(9), 3955-3958 (2014-06-18)
The melastatin-related transient receptor potential 7 channel (TRPM7) is a nonselective cation channel that has been shown to promote tumor metastasis and progression. In this study, we determined the expression of TRPM7 in ovarian carcinomas and investigated its possible prognostic
Ebru Onalan Etem et al.
Journal of receptor and signal transduction research, 34(4), 317-324 (2014-03-22)
Hyperhomocysteinemia (HHcy) is associated with neurodegenerative diseases. Transient receptor potential melastatin (TRPM2) and TRPM7 channels may be activated by oxidative stress. Hydrated C(60) fullerene (C(60)HyFn) have recently gained considerable attention as promising candidates for neurodegenerative states. We aimed to examine

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