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SAB2500895

Sigma-Aldrich

Anti-RPE65 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-LCA2, Anti-RP20, Anti-Rd12, Anti-Retinal pigment epithelium-specific protein 65 kDa, Anti-SRPE65

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, canine

technique(s)

indirect ELISA: suitable
western blot: suitable

UniProt accession no.

Q16518

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RPE65(6121)

Immunogen

Peptide with sequence C-EVKKNARKAPQPE from the internal region of the protein sequence according to NP_000320.1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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GHS07

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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Xueting Luo et al.
Disease models & mechanisms, 11(4) (2018-04-07)
Subretinal fibrosis results in local destruction of retinal structures and permanent vision loss, representing the end stage of neovascular age-related macular degeneration (AMD). Histological examination of fibrotic specimens from AMD patients has uncovered a wide range of cellular and acellular
Hiba Amer Alsaeedi et al.
Journal of photochemistry and photobiology. B, Biology, 198, 111561-111561 (2019-07-29)
Blindness and vision loss contribute to irreversible retinal degeneration, and cellular therapy for retinal cell replacement has the potential to treat individuals who have lost light sensitive photoreceptors in the retina. Retinal cells are well characterized in function, and are
Giorgia Fanelli et al.
Scientific reports, 7(1), 14625-14625 (2017-11-09)
Age-related macular degeneration (AMD) is a major cause of blindness and is associated with complement dysregulation. The disease is a potential target for stem cell therapy but success is likely to be limited by the inflammatory response. We investigated the
Rajalekshmy Shyam et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(41), 10882-10887 (2017-09-07)
Carotenoids are plant-derived pigment molecules that vertebrates cannot synthesize de novo that protect the fovea of the primate retina from oxidative stress and light damage.
Xiaoping Qi et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 25(4), 917-927 (2017-02-17)
Bone marrow stem and progenitor cells can differentiate into a range of non-hematopoietic cell types, including retinal pigment epithelium (RPE)-like cells. In this study, we programmed bone marrow-derived cells (BMDCs) ex vivo by inserting a stable RPE65 transgene using a lentiviral vector.
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