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S7070

Sigma-Aldrich

Anti-Semaphorin 6A antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-Sema 6A

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About This Item

MDL number:
MFCD07784886
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

Quality Level

500

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse

technique(s)

direct ELISA: 0.5-1 μg/mL using rmWnt-1
immunohistochemistry: 2-5 μg/mL
western blot: 0.1-0.2 μg/mL using rmWnt-1

UniProt accession no.

O35464

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

mouse ... Sema6a(20358)

Specificity

This antibody shows ~25% cross-reactivity with rhSema 6A and less than 1% cross-reactivity with rhSema 3A, rhSema 3B, rmSema 3C, rmSema 3F, and rmSema 7A.

Immunogen

Sf21-derived, recombinant mouse semaphorin 6A (rmSema 6A).

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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Anne Eichmann et al.
Current opinion in neurobiology, 15(1), 108-115 (2005-02-22)
Blood vessels and nerves are structurally similar complex branched systems. Their guidance must be exquisitely regulated to ensure proper wiring of both networks. Recent results showed that specialized endothelial cells, resembling axonal growth cones, form the tips of growing capillaries.
Joris de Wit et al.
Progress in neurobiology, 71(2-3), 249-267 (2003-12-23)
In the developing nervous system, extending axons are directed towards their appropriate targets by a myriad of attractive and repulsive guidance cues. Work in the past decade has significantly advanced our understanding of these molecules and has made it increasingly
Gera Neufeld et al.
Frontiers in bioscience : a journal and virtual library, 10, 751-760 (2004-12-01)
The semaphorins are the products of a large family of genes currently containing more than 30 members. These genes are divided into eight classes of which classes 1, 2 and 8 contain invertebrate and viral semaphorins, while classes 3-7 contain
Roberto Fiore et al.
Frontiers in bioscience : a journal and virtual library, 8, s484-s499 (2003-04-18)
The wiring of the nervous system is established through a progressive refinement of the choices made by a growing axon. The growth cone is a highly motile structure at the tip of the axon that integrates the multitude of signals

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