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P6744

Sigma-Aldrich

Picric acid solution

1.3% in H2O (saturated)

Synonym(s):

2,4,6-Trinitrophenol

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About This Item

Linear Formula:
(O2N)3C6H2OH
CAS Number:
88-89-1
Molecular Weight:
229.10
Beilstein/REAXYS Number:
423400
MDL number:
MFCD00007102
UNSPSC Code:
12171500
PubChem Substance ID:
24898790
NACRES:
NA.47

form

liquid

Quality Level

200

concentration

1.3% in H2O (saturated)

color

yellow to very dark yellow

density

1.080 g/cm3

application(s)

hematology
histology

storage temp.

room temp

SMILES string

Oc1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O

InChI

1S/C6H3N3O7/c10-6-4(8(13)14)1-3(7(11)12)2-5(6)9(15)16/h1-2,10H

InChI key

OXNIZHLAWKMVMX-UHFFFAOYSA-N

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General description

Picric acid is a polynitrated aromatic acid. It dissolves in water to form a solution with low pH (pH 2.0). It interacts with basic groups of proteins, forms salts and coagulates them. Fixation with picric acid gives a bright stain, but there might be a loss of nucleic acids due to the low pH of the solution.
Picric acid is anionic and has a low molecular weight.

Application

Picric acid is commonly used as a fixative and staining reagent in forensic and histological applications. It is a general cytoplasmic stain, connective tissue fiber stain, and a fixative for tissues.
  • It is a component of picrosirius red which is used to stain collagen.
  • Bouin’s fluid which also comprises picric acid is a fixative for nuclei and connective tissue.
  • It can be used as a colorimetric reagent in creatinine determination assay.

supp_hazards

EUH001

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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