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L1750

Sigma-Aldrich

L-(+)-Lactic acid

≥98%

Synonym(s):

(S)-2-Hydroxypropionic acid, Sarcolactic acid

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About This Item

Empirical Formula (Hill Notation):
C3H6O3
CAS Number:
79-33-4
Molecular Weight:
90.08
Beilstein/REAXYS Number:
1720251
EC Number:
201-196-2
MDL number:
MFCD00064266
UNSPSC Code:
12161700
PubChem Substance ID:
24896289
NACRES:
NA.25

Quality Level

200

assay

≥98%

antibiotic activity spectrum

Gram-negative bacteria

mode of action

cell membrane | interferes

storage temp.

2-8°C

SMILES string

C[C@H](O)C(O)=O

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1

InChI key

JVTAAEKCZFNVCJ-REOHCLBHSA-N

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General description

L-(+)-Lactic acid is the only naturally occurring lactic acid in humans and mammals. Commercially, few bacteria like Lactobacillus casei, L. delbrueckii, Streptococcus lactis produces L-Lactic acid by fermentation process. Lactic acid activates hydroxycarboxylic acid receptor, G-protein coupled receptor 81 (GPR81).

Application

Lactic acid has been used:
  • as a component in substrate solution II for lactate dehydrogenase reaction
  • as an additive in storage solution A
  • as a supplement in the artificial gastric juice preparation for evaluation of degree of resistance Lactobacillus to the gastric stresses

Biochem/physiol Actions

L-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1C

supp_hazards

EUH071

Storage Class

8A - Combustible, corrosive hazardous materials

wgk_germany

WGK 1

flash_point_f

230.0 °F - closed cup

flash_point_c

110.00 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lactic acid United States Pharmacopeia (USP) Reference Standard

USP

1356734

Lactic acid

L-(+)-Lactic acid solution 30% in H2O (by weight)

Sigma-Aldrich

L1875

L-(+)-Lactic acid solution

Lactic acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1215

Lactic acid

Sodium L-lactate ~98%

Sigma-Aldrich

L7022

Sodium L-lactate

Sodium L-lactate ≥99.0% (NT)

Sigma-Aldrich

71718

Sodium L-lactate

L-(+)-Lactic acid solution ~40% in H2O

Sigma-Aldrich

69780

L-(+)-Lactic acid solution

The isolation, identification and analyzes of Lactobacillus genus bacteria with probiotic potential
Advances in Microbiology, Infectious Diseases and Public Health, 73-73 (2016)
Mastoparan as a G protein activator
Animal Toxins: Facts and Protocols, 120-121 (2000)
Cell-free transcription of SV40
SV40 protocols, 73-73 (2001)
A History of Lactic Acid Making: A Chapter in the History of Biotechnology (1990)
International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands
Davenport AP, et al.
Pharmacological Reviews, 65(3), 967-986 (2013)
View All Related Papers

Protocols

LC/MS Analysis of Lactic Acid Enantiomers in Urine on Astec® CHIROBIOTIC® R

Separation of L-(+)-Lactic acid, analytical standard; D-(−)-Lactic acid, 93-107%

Chromatograms

application for HPLCapplication for HPLC

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