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Sigma-Aldrich

Intralipid

20%, emulsion

Synonym(s):

Phospholipid stabilized soybean oil

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

form

emulsion

Quality Level

concentration

20%

color

white

storage temp.

2-8°C

Application

Intralipid has been used:
  • for testing its optical properties to be used as scattering medium for tissue phantom generation
  • as a component of agarose gel phantom to reduce scatter coefficients and background absorption
  • in infusion into mice in hyperinsulinemic-euglycemic clamps studies to evaluate its effect on nonesterified free fatty acids (NEFA) circulation

Biochem/physiol Actions

Intralipid is a lipid emulsion comprising soybean oil. It favors proinflammatory cytokines production and is recommended for the treatment of immune-mediated pregnancy and implantation failure. In parenteral nutrition, intralipid is the source of fats. It elicits protection in heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening. Intralipid is an effective alternative for intravenous immunoglobulin and improves bioavailability of platinum based anti-cancer drugs.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simultaneous multiwavelength laminar optical tomography
Burgess SA, et al.
Optics Letters, 33(22), 2710-2712 (2008)
Sean R Donohue et al.
Journal of medicinal chemistry, 51(18), 5833-5842 (2008-09-20)
We have reported that [methyl- (11)C] (3 R,5 R)-5-(3-methoxyphenyl)-3-[(R)-1-phenylethylamino]-1-(4-trifluoromethylphenyl)pyrrolidin-2-one ([(11)C] 8, [(11)C]MePPEP) binds with high selectivity to cannabinoid type-1 (CB 1) receptors in monkey brain in vivo. We now describe the synthesis of 8 and four analogues, namely, the 4-fluorophenyl
Evaluating the utility of intralipid infusion to improve live birth rates in patients with recurrent pregnancy loss or recurrent implantation failure
Martini AE, et al.
13th ACS Winter Fluorine Conference, paper No. 8, 11(3), 261-261 (2018)
Broadband spectroscopy for characterization of tissue-like phantom optical properties
Shahin A and Bachir W
Polish journal of medical physics and engineering, 23(4), 121-126 (2017)
The Importance of Intralipid in Heart Protection: A Brief Review
Dizaj SM
Journal of Anesthesia and Surgery, 4(1), 0-0 (2017)

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