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F5384

Sigma-Aldrich

Anti-Human IgM (μ-chain specific)−FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Goat Anti-Human IgM (μ-chain specific)−Fluorescein isothiocyanate

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

goat

Quality Level

conjugate

FITC conjugate

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

technique(s)

direct immunofluorescence: 1:32

storage temp.

2-8°C

target post-translational modification

unmodified

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General description

The product binds human IgM; but does not bind other human Igs.

Application

Anti-Human IgM (μ-chain specific)-FITC antibody produced in goat was used as secondary antibody in serodiagnosis of Lyme disease based on seroreactivity against Borrelia spirochaetes.

Biochem/physiol Actions

IgM antibodies are present as pentamers in the serum and are produced in response to antigens.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Nayoung Ko et al.
Scientific reports, 12(1), 9611-9611 (2022-06-11)
Pig-to-human organ transplantation is a feasible solution to resolve the shortage of organ donors for patients that wait for transplantation. To overcome immunological rejection, which is the main hurdle in pig-to-human xenotransplantation, various engineered transgenic pigs have been developed. Ablation
Jingtao Cui et al.
PloS one, 13(11), e0206995-e0206995 (2018-11-08)
Chlamydia pneumoniae (C. pneumoniae) is an obligate intracellular bacterium and a human pathogen that causes respiratory infectious diseases. More than 50% of the adult population worldwide was once infected with C. pneumoniae, but investigations into this topic are insufficient in
Haiyan Xu et al.
Microbiology and immunology, 58(8), 439-448 (2014-06-17)
The objective of the present study was to explore the correlation between the BAFF signal and HCMV-TLR activation in RTx recipients complicated by HCMV. Peripheral blood (anticoagulated by EDTA-Na2 ) and urine of 113 RTx recipients were collected; healthy volunteers
First detection and molecular identification of Borrelia garinii isolated from human skin in Taiwan.
Li-Lian Chao et al.
Journal of medical microbiology, 59(Pt 2), 254-257 (2009-11-17)
Wensha Yang et al.
The Analyst, 132(4), 296-306 (2007-06-08)
The integration of biological molecules with semiconducting materials such as silicon and diamond has great potential for the development of new types of bioelectronic devices, such as biosensors and bioactuators. We have investigated the electrical properties of the antibody-antigen modified

Articles

Antibody-based serology tests are useful in identifying subjects with an adaptive immune response to the SARS-CoV-2 virus. Anti-human immunoglobulin antibodies allow for quick and simple, yet reliable assays with easy readouts and can also be adapted for high-throughput screening.

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