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D9565

Sigma-Aldrich

β-Defensin 1 human

≥98% (HPLC and SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)

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About This Item

MDL number:
UNSPSC Code:
12352202
NACRES:
NA.32

recombinant

expressed in E. coli

Quality Level

assay

≥98% (HPLC and SDS-PAGE)

form

lyophilized powder (from 10 mM acetic acid)

mol wt

estimated mol wt 3.9 kDa

UniProt accession no.

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
fungi
viruses

mode of action

cell wall synthesis | interferes

storage temp.

−20°C

Gene Information

human ... DEFB1(1672)

Amino Acid Sequence

Asp-His-Tyr-Asn-Cys-Val-Ser-Ser-Gly-Gly-Gln-Cys-Leu-Tyr-Ser-Ala-Cys-Pro-Ile-Phe-Thr-Lys-Ile-Gln-Gly-Thr-Cys-Tyr-Arg-Gly-Lys-Ala-Lys-Cys-Cys-Lys [Disulfide bridges 5-34, 12-27, and 17-35]

General description

Chemical structure: peptide

Biochem/physiol Actions

A small cationic peptide which demonstrates anti-microbial activity. Originally isolated from human plasma, this substance is constitutively expressed in mucosal membrane epithelium.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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