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C9008

Sigma-Aldrich

p-Coumaric acid

≥98.0% (HPLC)

Synonym(s):

trans-4-Hydroxycinnamic acid

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About This Item

Linear Formula:
HOC6H4CH=CHCO2H
CAS Number:
501-98-4
Molecular Weight:
164.16
Beilstein/REAXYS Number:
2207383
MDL number:
MFCD00004399
UNSPSC Code:
12171500
PubChem Substance ID:
24893127
NACRES:
NA.47

Quality Level

200

assay

≥98.0% (HPLC)

form

powder

color

white to yellow

mp

214 °C (dec.) (lit.)

solubility

ethanol: 50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

OC(=O)\C=C\c1ccc(O)cc1

InChI

1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3+

InChI key

NGSWKAQJJWESNS-ZZXKWVIFSA-N

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Application

p-Coumaric acid has been used as a component of chemiluminescent substrate for protein detection in western blotting.

Biochem/physiol Actions

In western blot, p-coumaric is also used as an enhancer in chemiluminescent substrate.
Hydroxycinnamic acid found in many fruits and vegetables.

Other Notes

Predominantly trans isomer.

related product

Product No.
Description
Pricing

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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trans-p-Coumaric acid phyproof® Reference Substance

PHL89498

trans-p-Coumaric acid

TGF-beta receptor levels regulate the specificity of signaling pathway activation and biological effects of TGF-beta.
Rojas A, et al.
Biochimica et Biophysica Acta, 1793, 1165-1173 (2009)
p-Coumaric acid, a common dietary phenol, inhibits platelet activity in vitro and in vivo.
Luceri C, et al.
The British Journal of Nutrition, 97, 458-463 (2007)
p-Coumaric acid kills bacteria through dual damage mechanisms.
Zaixiang L, et al.
Food Control, 25, 550-554 (2012)
Enhanced chemiluminescence (ECL) for routine immunoblotting: An inexpensive alternative to commercially available kits.
Mruk DD and Cheng CY
Spermatogenesis, 1, 121-122 (2011)
Inflammation triggers high mobility group box 1 (HMGB1) secretion in adipose tissue, a potential link to obesity.
Gunasekaran MK, et al.
Cytokine, 64, 103-111 (2013)
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