C3860
Cytochrome P450 human
1B1 Isozyme Microsomes, with P450 Reductase, recombinant, expressed in baculovirus infected insect cells (BTI-TN-5B1-4)
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About This Item
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biological source
human
Quality Level
recombinant
expressed in baculovirus infected insect cells (BTI-TN-5B1-4)
form
solution
mol wt
45-60 kDa
packaging
vial of 0.5 nmol
UniProt accession no.
application(s)
cell analysis
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... CYP1B1(1545)
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Biochem/physiol Actions
Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules, both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds (drugs or toxins). Some isoforms have narrow substrate specificity, while others are promiscuous.
Unit Definition
One unit will reduce 1 nanomole of cytochrome C per minute at pH 7.4 at 37 deg C.
Physical form
Solution in 100 mM potassium phosphate buffer, pH 7.4.
Preparation Note
Microsomes containing human CYP1B1 and recombinant human NADPH-P450 reductase.
Analysis Note
Tested for the ability to catalyze the 7-deethylation of ethoxyresorufin.
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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