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Y0000483

Hyoscine

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(−)-Scopolamine

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About This Item

Empirical Formula (Hill Notation):
C17H21NO4
CAS Number:
51-34-3
Molecular Weight:
303.35
EC Number:
200-090-3
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

hyoscine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11?,12-,13-,14+,15?,16?/m1/s1

InChI key

STECJAGHUSJQJN-MKXJHAPZSA-N

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hyoscine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

H1500000

Hyoscine hydrobromide, European Pharmacopoeia (EP) Reference Standard

Y0000448

Hyoscine hydrobromide impurity B, European Pharmacopoeia (EP) Reference Standard

Y0000484

Hyoscine impurity A, European Pharmacopoeia (EP) Reference Standard

H1450000

Hyoscine butylbromide, European Pharmacopoeia (EP) Reference Standard

1610001

Scopolamine hydrobromide, United States Pharmacopeia (USP) Reference Standard

PHR1470

Scopolamine Hydrobromide, Pharmaceutical Secondary Standard; Certified Reference Material

BP198

Hyoscine butylbromide, British Pharmacopoeia (BP) Reference Standard

BP199

Hyoscine hydrobromide, British Pharmacopoeia (BP) Reference Standard

Y0001983

Hyoscine butylbromide for system suitability, European Pharmacopoeia (EP) Reference Standard

pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Sens. 1

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

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Scopolamine hydrobromide meets USP testing specifications

Sigma-Aldrich

S0929

Scopolamine hydrobromide

(−)-Scopolamine hydrobromide trihydrate ≥98% (HPLC), powder

Sigma-Aldrich

S1875

(−)-Scopolamine hydrobromide trihydrate

USP

USP

1335010

Hyoscyamine Related Compound A

USP

USP

1335009

Hyoscyamine sulfate

(−)-Scopolamine N-butyl bromide ≥98% (TLC), powder

Sigma-Aldrich

S7882

(−)-Scopolamine N-butyl bromide

Tropic acid 98%

Sigma-Aldrich

T89206

Tropic acid

(-)-Scopolamine hydrobromide solution 1.0 mg/mL in acetonitrile: water (9:1) (as free base), certified reference material, ampule of 1 mL, Cerilliant®

Supelco

S-098

(-)-Scopolamine hydrobromide solution

Daniela Braida et al.
Behavioural brain research, 242, 95-101 (2013-01-08)
Selective attention can be assessed with the novel object recognition (NOR) test. In the standard version of this test the selection of objects to be used is critical. We created a modified version of NOR, the virtual object recognition test
Juan-Juan Yan et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(21), 3293-3296 (2013-02-13)
To investigate the effect of Dingzhixiao Wan (DZXW), a classic traditional Chinese medicine formula consisting of Acorus tatarinowii, Polygala tenuifolia, Poria cocos and Panax ginseng in a proportion of 2: 2: 3: 3, on learning-memory impairment induced by scopolamine and
Thomas H Dohlman et al.
Investigative ophthalmology & visual science, 54(6), 4081-4091 (2013-05-25)
Th17 cells are believed to be the primary effector cells in the pathogenesis of dry eye disease (DED). However, the mechanisms by which Th17 cells migrate from the lymphoid tissues to the ocular surface are unknown. The purpose of this
Yihe Chen et al.
Investigative ophthalmology & visual science, 54(4), 2457-2464 (2013-03-14)
A majority of experimental data on dry eye disease (DED) immunopathogenesis have been derived from a murine model of DED that combines desiccating environmental stress with systemic muscarinic acetylcholine receptor (mAChR) inhibition. However, to our knowledge the effects of pharmacologic
Young Jin Jang et al.
Behavioural brain research, 245, 113-119 (2013-02-19)
Several human studies have reported that coffee consumption improves cognitive performance. In the present study, we investigated whether instant decaffeinated coffee also ameliorates cognitive performance and attenuates the detrimental effects of scopolamine on memory. Memory performance was evaluated in Morris
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