Skip to Content
MilliporeSigma
All Photos(1)

Documents

PHR2838

Supelco

Ampicillin

pharmaceutical secondary standard, certified reference material

Synonym(s):

Ampicillin, D-(−)-α-Aminobenzylpenicillin

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C16H19N3O4S
CAS Number:
69-53-4
Molecular Weight:
349.40
Beilstein/REAXYS Number:
1090925
MDL number:
MFCD00005175
UNSPSC Code:
41116107

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

agency

traceable to Ph. Eur. A1000000
traceable to USP 1033000

description

Pharmaceutical Secondary Standard; Certified Reference Material

API family

ampicillin

form

solid

packaging

pkg of 500 mg

mp

208 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3)C(O)=O

InChI

1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1

InChI key

AVKUERGKIZMTKX-NJBDSQKTSA-N

Related Categories

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Mode of Action: Ampicillin is a semisynthetic penicillin and a ß-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane.

Mode of Resistance: Administration with ß-lactamase cleaves the ß-lactam ring of Ampicillin and inactivates it.

Antimicrobial Spectrum: Effective against both Gram-positive (similar to benzylpenicillin) and Gram-negative bacteria (similar to tetracyclines and chloramphenicol.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

related product

Product No.
Description
Pricing

A1100000

Ampicillin trihydrate, European Pharmacopoeia (EP) Reference Standard

A1000000

Ampicillin, anhydrous, European Pharmacopoeia (EP) Reference Standard

PHR1393

Ampicillin Trihydrate, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1424

Ampicillin Sodium, Pharmaceutical Secondary Standard; Certified Reference Material

1033203

Ampicillin sodium, United States Pharmacopeia (USP) Reference Standard

1033407

Ampicillin trihydrate, United States Pharmacopeia (USP) Reference Standard

1033247

Ampicillin System Suitability Mixture, United States Pharmacopeia (USP) Reference Standard

BP785

Anhydrous ampicillin, British Pharmacopoeia (BP) Reference Standard

BP021

Ampicillin trihydrate, British Pharmacopoeia (BP) Reference Standard

PHR9060

D-(−)-α-Phenylglycine, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR9105

(2R)-2-[(2,2-Dimethylpropanoyl)amino]-2-phenylacetic acid, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAC6678

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service