PHR1274
Melamine
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
2,4,6-Triamino-1,3,5-triazine, sym-Triaminotriazine
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About This Item
Empirical Formula (Hill Notation):
C3H6N6
CAS Number:
Molecular Weight:
126.12
Beilstein/REAXYS Number:
124341
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
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grade
certified reference material
pharmaceutical secondary standard
Quality Level
agency
traceable to USP 1379183
API family
melamine
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
>300 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
Nc1nc(N)nc(N)n1
InChI
1S/C3H6N6/c4-1-7-2(5)9-3(6)8-1/h(H6,4,5,6,7,8,9)
InChI key
JDSHMPZPIAZGSV-UHFFFAOYSA-N
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General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Melamine is a nitrogen-rich chemical employed in the production of plastics, resins, laminates, adhesives as well as flame retardants. It may also be utilized as a fertilizer. It is one of the metabolites of cyromazine, which is approved for use as an insecticide on a wide range of vegetable crops.
Melamine is a nitrogen-rich chemical employed in the production of plastics, resins, laminates, adhesives as well as flame retardants. It may also be utilized as a fertilizer. It is one of the metabolites of cyromazine, which is approved for use as an insecticide on a wide range of vegetable crops.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAC3464 in the slot below. This is an example certificate only and may not be the lot that you receive.
Recommended products
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
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signalword
Warning
hcodes
Hazard Classifications
Carc. 2 - Repr. 2 - STOT RE 2
target_organs
Urinary tract
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
572.0 °F - closed cup
flash_point_c
300 °C - closed cup
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Method development and validation for melamine and its derivatives in rice concentrates by liquid chromatography. Application to animal feed samples
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Analytical and Bioanalytical Chemistry, 392(3), 523-531 (2008)
Yanhua Zhao et al.
Talanta, 113, 7-13 (2013-05-28)
Silver nanoparticles coated amino modified polystyrene microspheres (PS-NH2/Ag NPs) with extremely high surface enhanced Raman scattering (SERS) activity and uniform surface morphology were created by precise controlling of deposition time. Nanojets that were formed underneath the individual microspheres could be
Yu-Chang Tyan et al.
Analytical and bioanalytical chemistry, 395(3), 729-735 (2009-08-12)
In the summer of 2008, serious illnesses and deaths of babies in China were linked to melamine-tainted powdered infant formula. Melamine contains several metabolites, such as ammeline, ammelide, and cyanuric acid, and has been used for the adulteration of foods
Sana Jawaid et al.
Food chemistry, 141(3), 3066-3071 (2013-07-23)
Melamine is a nitrogenous chemical substance used principally as a starting material for the manufacture of synthetic resins. Due to its very high proportion of nitrogen melamine has been added illegitimately to foods and feeds to increase the measured protein
Lingjie Kong et al.
Optics letters, 38(2), 145-147 (2013-03-05)
Stimulated Raman scattering (SRS) microscopy allows label-free chemical imaging based on vibrational spectroscopy. Narrowband excitation with picosecond lasers creates the highest signal levels and enables imaging speeds up to video-rate, but it sacrifices chemical specificity in samples with overlapping bands
Protocols
Separation of Melamine; 1,1-Dimethylbiguanide hydrochloride
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