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packaging
pkg of 4.08 g
manufacturer/tradename
NIST®
technique(s)
mass spectrometry (MS): suitable
application(s)
clinical testing
storage temp.
−70°C
Related Categories
General description
A unit of Hormones in Frozen Human Serum standard reference material (SRM) consists of two vials each of two materials: one from a pool of healthy, premenopausal adult females and one from a pool of healthy adult males. The certified values of the SRM were determined using higher-order reference measurement procedures calibrated with high-purity chemical reference standards in combination with higher-order measurement procedures conducted by the CDC. The uncertainties are expanded uncertainties at the 95 % level of confidence. The certified values of the SRM, apply only to serum thawed to room temperature, 20 °C to 25 °C.
SRM 971a_cert
SRM 971a _SDS
SRM 971a_cert
SRM 971a _SDS
Application
ThisNIST SRM 971a is intended primarily for use in evaluating the accuracy of procedures for the determination of the steroid hormones cortisol, progesterone, and testosterone, and thyroid hormones total thyroxine (T4), and total 3,3′,5-triiodothyronine (T3) in human serum.
It is also intended for use in validating working or secondary reference materials.
It is also intended for use in validating working or secondary reference materials.
Features and Benefits
- A unit of SRM contains two vials of each material. Each vial approximately contains 2 mL of human serum
- Both materials in the SRM are unfortified
Other Notes
- SRM 971a is intended for research use.
- The serum is shipped frozen (on dry ice) and, upon receipt, should be stored frozen until ready for use.
- Expiration details and storage and use instructions are provided on the NIST certificate
- Notes on biomaterial handling, disposal, and transport documented in MSDS
Legal Information
NIST is a registered trademark of National Institute of Standards and Technology
SRM is a registered trademark of National Institute of Standards and Technology
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Sung-Eun Cho et al.
Annals of laboratory medicine, 43(1), 19-28 (2022-09-01)
Mass spectrometry methods exhibit higher accuracy and lower variability than immunoassays at low testosterone concentrations. We developed and validated an ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) assay for quantifying serum total testosterone. We used an ExionLC UPLC (Sciex, Framingham, MA
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