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M6880

Sigma-Aldrich

Malachite Green oxalate salt

Powder, crystals or chunks

Synonym(s):

N,N,N′,N′-Tetramethyl-4,4′-diaminotriphenylcarbenium oxalate, Basic Green 4

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About This Item

Empirical Formula (Hill Notation):
C23H25N2 · C2HO4 · 0.5C2H2O4
CAS Number:
2437-29-8
Molecular Weight:
463.50
Colour Index Number:
42000
Beilstein/REAXYS Number:
3644550
EC Number:
219-441-7
UNSPSC Code:
12171500
PubChem Substance ID:
24897123
NACRES:
NA.47

product name

Malachite Green oxalate salt, Technical grade

grade

technical grade

Quality Level

200

form

powder, crystals or chunks

color

metallic green

solubility

water: 1 mg/mL

λmax

616-620 nm in water

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

C[N+](C)=C1C=CC(C=C1)=C(C2=CC=C(N(C)C)C=C2)C3=CC=CC=C3.[O-]C(C(O)=O)=O

InChI

1S/C23H25N2.C2H2O4/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4;3-1(4)2(5)6/h5-17H,1-4H3;(H,3,4)(H,5,6)/q+1;/p-1

InChI key

REZFCYOVFCJTDG-UHFFFAOYSA-M

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General description

The release of phosphate or pyrophosphate in an enzymatic reaction can be detected by malachite green and is measured spectrometrically at 660nm.

Application

Malachite Green oxalate salt has been used in biliary phospholipid analysis.
Malachite Green oxalate salt has been used:
  • in the preparation of malachite green-ammonium molybdate reagent, as a stop solution for starch synthase activity assay
  • to terminate the phosphatase and tensin homologue deleted on chromosome 10 (PTEN) inhibition assay using phosphatidylinositol (3,4,5) triphosphate (PI(3,4,5)P3) as substrate
  • to determine trypanothione synthetase activity to measure inorganic phosphate release from adenosine triphosphate (ATP) during catalysis

Biochem/physiol Actions

Malachite green is used in the treatment of fungal and parasitic infections in fish.

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Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 2

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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