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95082

Supelco

Chrysin

analytical standard

Synonym(s):

5,7-Dihydroxyflavone

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About This Item

Empirical Formula (Hill Notation):
C15H10O4
CAS Number:
480-40-0
Molecular Weight:
254.24
Beilstein/REAXYS Number:
233276
EC Number:
207-549-7
MDL number:
MFCD00006834
UNSPSC Code:
85151701
PubChem Substance ID:
329770416
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥98% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

284-286 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccccc3

InChI

1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H

InChI key

RTIXKCRFFJGDFG-UHFFFAOYSA-N

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General description

Chrysin is a naturally occurring mono-flavonoid , which is present in plant cells involved in photosynthesis. It may possess a broad spectrum of pharmacological properties like antioxidant, anti-viral, anti-inflammatory, anxiolytic and vasodilatory effects.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

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Possible anxiolytic effects of chrysin, a central benzodiazepine receptor ligand isolated from Passiflora coerulea
Wolfman C, et al.
Pharmacology, Biochemistry, and Behavior, 47(1), 1-4 (1994)
G A R Oliveira et al.
Journal of toxicology and environmental health. Part A, 75(16-17), 1000-1011 (2012-08-03)
Chrysin is one of the natural flavonoids present in plants, and large amounts are present in honey and propolis. In addition to anticancer, antioxidation, and anti-inflammatory activities, chrysin has also been reported to be an inhibitor of aromatase, an enzyme
Alexandrine During et al.
Biochemical pharmacology, 86(12), 1739-1746 (2013-10-19)
The aim of this study was to investigate whether methoxylated flavones versus their unmethylated analogs can modulate the intestinal inflammatory response. Flavone effects were assessed on soluble pro-inflammatory mediator (IL-8, IL-6, macrophage chemoattractant protein-1 (MCP-1), and cyclooxygenase-2 (COX-2)-derived PGE2) production
Rehan Khan et al.
The British journal of nutrition, 108(9), 1574-1585 (2012-02-09)
Cisplatin (cis-diamminedichloroplatinum (II) (CDDP)) is a commonly used chemotherapeutic drug for the treatment of numerous forms of cancer, but it has pronounced adverse effects, namely nephrotoxicity, ototoxicity, neurotoxicity, hepatotoxicity, diarrhoea and nausea. CDDP-induced emesis and diarrhoea are also marked toxicities
Xiao-Li He et al.
European journal of pharmacology, 680(1-3), 41-48 (2012-02-09)
Chronic cerebral hypoperfusion, induced by permanent occlusion of bilateral common carotid arteries (2VO), is related to neurological disorders and contributes to cognitive decline. Chrysin (5,7-dihydroxyflavone) is an important member of the flavonoid family. The aim of this study is to
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