Skip to Content
MilliporeSigma
All Photos(1)

Documents

07969

Sigma-Aldrich

O-(2-Aminoethyl)polyethylene glycol 3,000

Mp 3,000

Synonym(s):

Aminopolyethylene glycol

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
NH2(CH2CH2O)nH
CAS Number:
32130-27-1
MDL number:
MFCD00286223
UNSPSC Code:
12162002
PubChem Substance ID:
24846131
NACRES:
NA.22

mol wt

Mp 3,000

Quality Level

100

reaction suitability

reagent type: cross-linking reagent

Ω-end

hydroxyl

α-end

amine

SMILES string

[H]OCCN

Related Categories

General description

O-(2-Aminoethyl)polyethylene glycol is a heterobifunctional polyethylene glycol (hydroxyl-PEG-amine) useful in conjugation and crosslinking reactions.

Application

O-(2-Aminoethyl)polyethylene glycol has been used to synthesize PEG-poly(D,L-lactide-co-glycolide) (PEG-PLGA) conjugate for use in the synthesis of PLGA-based nanoparticles.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 6

1 of 6

Methoxypolyethylene glycol amine 750

Sigma-Aldrich

07964

Methoxypolyethylene glycol amine

mPEG12-NH2

Sigma-Aldrich

JKA13003

mPEG12-NH2

m-dPEG®24-amine

Sigma-Aldrich

QBD10318

m-dPEG®24-amine

Poly(D,L-lactide-b-glycolide) lactide:glycolide 50:50 amine terminated, average Mn 5,000

Sigma-Aldrich

908517

Poly(D,L-lactide-b-glycolide) lactide:glycolide 50:50

Methoxypolyethylene glycol amine 5,000, extent of labeling: ≥0.17 mmol/g NH2 loading

Sigma-Aldrich

06679

Methoxypolyethylene glycol amine

Poly(ethylene glycol) methyl ether amine average Mn 500

Sigma-Aldrich

767565

Poly(ethylene glycol) methyl ether amine

Jeremiah A Johnson et al.
Macromolecules, 43(24), 10326-10335 (2011-05-03)
Graft-through ring-opening metathesis polymerization (ROMP) using ruthenium N-heterocyclic carbene catalysts has enabled the synthesis of bottle-brush polymers with unprecedented ease and control. Here we report the first bivalent-brush polymers; these materials were prepared by graft-through ROMP of drug-loaded polyethylene-glycol (PEG)
Angela X Gao et al.
ACS macro letters, 3(9), 854-857 (2014-09-23)
A panel of acid-labile bis-norbornene cross-linkers was synthesized and evaluated for the formation of acid-degradable brush-arm star polymers (BASPs) via the brush-first ring-opening metathesis polymerization (ROMP) method. An acetal-based cross-linker was identified that, when employed in conjunction with a poly(ethylene
Folic acid-decorated and PEGylated PLGA nanoparticles for improving the antitumour activity of 5-fluorouracil.
El-Hammadi
International Journal of Pharmaceutics, 516(1-2), 61-70 (2017)
Alan O Burts et al.
Macromolecular rapid communications, 35(2), 168-173 (2013-11-23)
This report describes the synthesis of miktoarm brush-arm star polymers (BASPs) from branched and linear norbornene-terminated macromonomers (MMs) via the brush-first ring-opening metathesis polymerization (ROMP) method. First, a polystyrene (PS)-branch-poly(lactic acid) (PLA) MM is synthesized via a combination of atom
Jeremiah A Johnson et al.
Journal of the American Chemical Society, 133(3), 559-566 (2010-12-15)
The combination of highly efficient polymerizations with modular "click" coupling reactions has enabled the synthesis of a wide variety of novel nanoscopic structures. Here we demonstrate the facile synthesis of a new class of clickable, branched nanostructures, polyethylene glycol (PEG)-branch-azide
View All Related Papers

Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service