MAB5654
Anti-Prox1 Antibody, clone 4G10
clone 4G10, Chemicon®, from mouse
Synonym(s):
Homeobox prospero-like protein PROX1
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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biological source
mouse
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
4G10, monoclonal
species reactivity
chicken, mouse, rat, human, lizard
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Prox1(19130)
Related Categories
Specificity
Prox1. By Western blot the antibody recognizes a ~83 kDa protein in fetal mouse brain lysate.
Immunogen
Recombinant human Prox1 protein.
Application
Anti-Prox1 Antibody, clone 4G10 is an antibody against Prox1 for use in WB, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Neuroscience
Neuronal & Glial Markers
Developmental Neuroscience
Neuronal & Glial Markers
Western blot: 2 μg/mL
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Target description
83 kDa
Linkage
Replaces: MABE488
Physical form
Format: Purified
Liquid in PBS with 0.1% sodium azide.
Protein A purified
Storage and Stability
Maintain at 2-8degC in undiluted aliquots for up to 6 months after date of receipt.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Certificates of Analysis (COA)
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Shogo Yoshihara et al.
Cell reports, 35(2), 108971-108971 (2021-04-15)
In schizophrenia (SCZ), neurons in the brain tend to undergo gross morphological changes, but the related molecular mechanism remains largely elusive. Using Kif3b+/- mice as a model with SCZ-like behaviors, we found that a high-betaine diet can significantly alleviate schizophrenic
Julia Holzmann et al.
Developmental neurobiology, 75(12), 1352-1367 (2015-03-20)
Neurogenesis in embryonic sympathetic ganglia involves neuroblasts that resume proliferation following neuronal differentiation. As cell cycle exit is not associated with neuronal differentiation, the identity of proliferating neuroblasts is incompletely understood. Here, we use sympathetic ganglia of chick embryos to
Prox1 regulates the notch1-mediated inhibition of neurogenesis.
Kaltezioti, V; Kouroupi, G; Oikonomaki, M; Mantouvalou, E; Stergiopoulos, A; Charonis et al.
PLoS Biology null
Baptiste N Jaeger et al.
Nature communications, 9(1), 3084-3084 (2018-08-08)
Activity-induced remodeling of neuronal circuits is critical for memory formation. This process relies in part on transcription, but neither the rate of activity nor baseline transcription is equal across neuronal cell types. In this study, we isolated mouse hippocampal populations
Xiaoren Chen et al.
Hybridoma (2005), 25(1), 27-33 (2006-02-16)
Prox1 is a divergent homeodomain protein important for the development of the lens, retina, liver, pancreas, and lymphatic vasculature. Prox1 expression is highly upregulated in transformed hepatocytes and has been used as a marker to distinguish lymphatic from blood vasculature.
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